Buprenorphine/naloxone vs methadone for the treatment of opioid use disorder

B. NOSYK ; J. E. MIN ; F. HOMAYRA ; M. KURZ ; B. C. GUERRA-ALEJOS ; R. YAN ; M. PISKE ; S. R. SEAMAN ; P. BACH ; S. GREENLAND ; M. E. KARIM ; U. SIEBERT ; J. BRUNEAU ; P. GUSTAFSON ; K. KAMPMAN ; P. T. KORTHUIS ; T. LOUGHIN ; L. C. MCCANDLESS ; R. W. PLATT ; K. T. SCHNEPEL ; M. E. SOCIAS | 2024
Dans Journal of the American Medical Association (Vol.332, n°21, December 3, 2024) Article : Périodique

Key points: Question: Is buprenorphine/naloxone associated with lower risk of treatment discontinuation and mortality compared with methadone? Findings: In this population-based retrospective cohort study that included 30?891 individuals initi[...]

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Cost-effectiveness of diacetylmorphine versus methadone for chronic opioid dependence refractory to treatment

B. NOSYK ; D. P. GUH ; N. J. BANSBACK ; E. OVIEDO-JOEKES ; S. BRISSETTE ; D. C. MARSH ; E. MEIKLEHAM ; M. T. SCHECHTER ; A. H. ANIS | 2012
Dans Canadian Medical Association Journal (Vol.184, n°6, April 3, 2012) Article : Périodique

BACKGROUND: Although diacetylmorphine has been proven to be more effective than methadone maintenance treatment for opioid dependence, its direct costs are higher. We compared the cost-effectiveness of diacetylmorphine and methadone maintenance [...]

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Defining dosing pattern characteristics of successful tapers following methadone maintenance treatment: results from a population-based retrospective cohort study

B. NOSYK ; H. SUN ; E. EVANS ; D. C. MARSH ; M. D. ANGLIN ; Y. I. HSER ; A. H. ANIS ; E. DAY, Auteur du commentaire | 2012
Dans Addiction (Vol.107, n°9, September 2012) Article : Périodique

Aims: To identify dose-tapering strategies associated with sustained success following methadone maintenance treatment (MMT). Design: Population-based retrospective cohort study. Setting: Linked administrative medication dispensation data fr[...]

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Double-blind injectable hydromorphone versus diacetylmorphine for the treatment of opioid dependence: a pilot study

E. OVIEDO-JOEKES ; D. GUH ; S. BRISSETTE ; D. C. MARSH ; B. NOSYK ; M. K. KRAUSZ ; A. A. ANIS ; M. T. SCHECHTER | 2010
Dans Journal of Substance Abuse Treatment (Vol.38, n°4, June 2010) Article : Périodique

Using data from the North American Opioid Maintenance Initiative study, a Phase III randomized and parallel arm trial, this pilot study is aimed at testing if treatment response with injectable hydromorphone differs compared to diacetylmorphine [...]

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Estimating the economic value of British Columbia's domestic cannabis market: Implications for provincial cannabis policy

D. WERB ; B. NOSYK ; T. KERR ; B. FISCHER ; J. MONTANER ; E. WOOD | 2012
Dans International Journal of Drug Policy (Vol.23, n°6, November 2012) Article : Périodique

Background: British Columbia (BC), Canada, is home to a large illegal cannabis industry that is known to contribute to substantial organized crime concerns. Although debates have emerged regarding the potential benefits of a legally regulated ma[...]

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Inability to access health and social services associated with mental health among people who inject drugs in a Canadian setting

L. WANG ; D. PANAGIOTOGLOU ; J. E. MIN ; K. DEBECK ; M. J. MILLOY ; T. KERR ; K. HAYASHI ; B. NOSYK | 2016
Dans Drug and Alcohol Dependence (Vol.168, November 2016) Article : Périodique

Background: People who inject drugs (PWID) face barriers to healthcare due to reasons including comorbidity. We evaluated access to health and social services by three of the most prevalent comorbid conditions among PWID: HIV, hepatitis C (HCV),[...]

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Increases in the availability of prescribed opioids in a Canadian setting

B. NOSYK ; B. D. L. MARSHALL ; B. FISCHER ; J. S. G. MONTANER ; E. WOOD ; T. KERR | 2012
Dans Drug and Alcohol Dependence (Vol.126, n°1-2, November 2012) Article : Périodique

Background: The nonmedical use of prescribed opioids (POs) has increased across North America over the past decade. Our objective was to identify changes in the availability of POs and other illicit drugs among drug users in a Canadian setting. [...]

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Opioid agonist treatment and risk of mortality during opioid overdose public health emergency: population based retrospective cohort study

L. A. PEARCE ; J. E. MIN ; M. PISKE ; H. ZHOU ; F. HOMAYRA ; A. SLAUNWHITE ; M. IRVINE ; G. MCGOWAN ; B. NOSYK | 2020
Dans British Medical Journal (Vol.368, n°8240, 4 April 2020) Article : Périodique

Objective: To compare the risk of mortality among people with opioid use disorder on and off opioid agonist treatment (OAT) in a setting with a high prevalence of illicitly manufactured fentanyl and other potent synthetic opioids in the illicit [...]

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The temporal relationship between drug supply indicators: an audit of international government surveillance systems

D. WERB ; T. KERR ; B. NOSYK ; S. STRATHDEE ; J. MONTANER ; E. WOOD | 2013
Dans BMJ Open (Vol.3, n°9, 2013) Article : Périodique

FRANÇAIS : Un groupe de chercheurs états-uniens et canadiens ont étudié les données fournies par sept programmes gouvernementaux de surveillance du marché des drogues illicites. Leur conclusion est sans appel : la lutte internationale menée con[...]

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