Prospective comparative assessment of buprenorphine overdose with heroin and methadone: Clinical characteristics and response to antidotal treatment

B. MEGARBANE ; A. BUISINE ; F. JACOBS ; D. RESIERE ; L. CHEVILLARD ; E. VICAUT ; F. J. BAUD | 2010
Dans Journal of Substance Abuse Treatment (Vol.38, n°4, June 2010) Article : Périodique

Buprenorphine is a partial opioid agonist with a “ceiling effect” for respiratory depression. Despite this, it has been associated with severe overdoses. Conflicting data exist regarding its response in overdose to naloxone. We compared clinical[...]

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