Modulation ot the immune system in cannabis users

R. PACIFICI ; P. ZUCCARO ; S. PICHINI ; P. N. ROSET ; POUDEVIDA S. ; M. FARRE ; J. SEGURA ; R. DE LA TORRE | 2003
Périodique

ENGLISH : Cannabis use was associated with a decrease in levels of IL-2, a TH1-type cytokine related to cell-mediated immunity, and an increase in levels of IL-10, a TH2-type cytokine related to humoral immunity. The decrease of proinflammator[...]

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Repeated doses administration of MDMA in humans: pharmacological effects and pharmacokinetics

M. FARRE ; R. DE LA TORRE ; B. O MATHUNA ; P. N. ROSET ; A. M. PEIRO ; M. TORRENS ; J. ORTUNO ; M. PUJADAS ; J. CAMI | 2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique

RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA, "ecstasy") is increasingly used by young people for its euphoric and empathic effects. MDMA presents non-linear pharmacokinetics, probably by inhibition of cytochrome P450 isoform 2D6. Users ar[...]

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