Assessing long-term effects of MDMA - Ecstasy

G. A. RICAURTE ; U. D. McCANN ; L. RENEMAN ; J. BOOIJ ; K. DE BRUIN ; J. B. REITSMA ; F. A. DE WOLFF ; W. BOUDEWIJN GUNNING ; G. J. DEN HEETEN ; W. VAN DEN BRINK | 2001
Périodique

ENGLISH : Background 3,4-methylenedioxymethamphetamine (MDMA or ecstasy) is a popular recreational drug that has been shown to damage brain serotonin neurons in high doses. However, effects of moderate MDMA use on serotonin neurons have not be[...]

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Effects of dose, sex, and long-term abstention from use on toxic effects of MDMA (ecstasy) on brain serotonin neurons

L. RENEMAN ; J. BOOIJ ; K. DE BRUIN ; J. B. REITSMA ; F. A. DE WOLFF ; GUNNING W. B. ; DEN HEETEN G. ; W. VAN DEN BRINK | 2001
Périodique

ENGLISH : Background: 3,4-methylenedioxymethamphetamine (MDMA or ecstasy) is a popular recreational drug that has been shown to damage brain serotonin neurons in high doses. However, effects of moderate MDMA use on serotonin neurons have not b[...]

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Mood disorders and serotonin transporter density in ecstasy users- the influence of long-term abstention, dose, and gender

M. M. L. DE WIN ; L. RENEMAN ; J. B. REITSMA ; G. J. DEN HEETEN ; J. BOOIJ ; W. VAN DEN BRINK | 2004
Dans Psychopharmacology (Vol.173, n°3-4, May 2004) Article : Périodique

RATIONALE: Neurotoxic effects of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") on the serotonin (5-HT) system have been described in animals and humans, but little is known about long-term effects of ecstasy use on mood. OBJECTIVES: To inv[...]

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Use of amphetamine by recreational users of ecstasy (MDMA) is associated with reduced striatal dopamine transporter densities: a [123I] b -CIT SPECT study - preliminary report

L. RENEMAN ; J. BOOIJ ; J. LAVALAYE ; K. DE BRUIN ; J. B. REITSMA ; W. BOUDEWIJN GUNNING ; G. J. DEN HEETEN ; W. VAN DEN BRINK | 2002
Dans Psychopharmacology (Vol.159, n°3, January 2002) Article : Périodique

RATIONALE. Tablets sold as ecstasy often contain not only 3,4-methylenedioxymethamphetamine (MDMA) but other compounds well known to cause doparninergic neurotoxicity, such as (meth)amphetamine. Furthermore, the use of ecstasy in the Netherlands[...]

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