
Auteur L. LEGGIO
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Documents disponibles écrits par cet auteur (8)

R. AGABIO ; J. M. A. SINCLAIR ; G. ADDOLORATO ; H. J. AUBIN ; E. M. BERAHA ; F. CAPUTO ; J. D. CHICK ; P. DE LA SELLE ; N. FRANCHITTO ; J. C. GARBUTT ; P. S. HABER ; M. HEYDTMAN ; P. JAURY ; A. R. LINGFORD-HUGHES ; K. C. MORLEY ; C. A. MULLER ; L. OWENS ; A. PASTOR ; L. M. PATERSON ; F. PELISSIER ; B. ROLLAND ; A. STAFFORD ; A. THOMPSON ; W. VAN DEN BRINK ; R. DE BEAUREPAIRE ; L. LEGGIO | 2018
Dans Lancet Psychiatry (The) (Vol.5, n°12, December 2018) Article : Périodique
S. MINOZZI ; G. R. LA ROSA ; F. SALIS ; A. CAMPOSERAGNA ; R. SAULLE ; L. LEGGIO ; R. AGABIO | 2025
Dans Cochrane Database of Systematic Reviews (n°3, 2025) Article : PériodiqueKey messages: Compared to psychosocial interventions alone, adding medications is probably safe and helpful for people with alcohol use disorder (AUD) in reducing alcohol use. Due to the limited number of available studies, we do not know if c[...]
S. M. EDWARDS ; G. A. KENNA ; R. M. SWIFT ; L. LEGGIO | 2011
Dans Current Pharmaceutical Design (Vol.17, n°14, May 2011) Article : PériodiqueHarmful alcohol use is a risk factor in more than 60 diseases and injuries resulting in approximately 2.5 million deaths per year worldwide. In the United States (US) and Europe, there are only a few medications approved for alcohol dependence ([...]
G. ADDOLORATO ; L. LEGGIO ; A. FERRULLI ; S. CARDONE ; G. BEDOGNI ; F. CAPUTO ; G. GASBARRINI ; R. LANDOLFI ; Baclofen Study Group | 2011
Dans Alcohol and Alcoholism (Vol.46, n°3, May-June 2011) Article : PériodiqueAIMS: To explore the effect of baclofen in a dose of 20 mg three times per day, compared with the already studied dose of 10 mg three times per day, in the treatment of alcohol dependence. METHODS: We present a secondary analysis of a 12-week do[...]
ENGLISH : Craving plays an important role in the pathogenesis of alcohol dependence and relapse. In this review we have tried to analyse how many contrasting theories have been formulated in order to clarify the concept of craving. Many comple[...]
M. AMIN-ESMAEILI ; M. FAROKHNIA ; R. SUSUKIDA ; L. LEGGIO ; R. M. JOHNSON ; R. M. CRUM ; R. MOJTABAI | 2024
Dans Addiction (Vol.119, n°5, May 2024) Article : PériodiqueBACKGROUND AND AIMS: Total abstinence has historically been the goal of treatment for substance use disorders; however, there is a growing recognition of the health benefits associated with reduced use as a harm reduction measure in stimulant us[...]
P. DANPANICHKUL ; K. DUANGSONK ; L. A. DIAZ ; V. L. CHEN ; P. RANGAN ; B. SUKPHUTANAN ; P. DUTTA ; O. WANICHTHANAOLAN ; V. RAMADOSS ; B. SIM ; D. TUNG ; N. SIRANART ; H. NORITAKE ; H. TAKAHASHI ; M. NOUREDDIN ; L. LEGGIO ; J. D. YANG ; M. B. FALLON ; J. P. ARAB ; G. S. WINDER ; S. LIANGPUNSAKUL ; J. L. MELLINGER ; K. WIJARNPREECHA | 2025
Dans Drug and Alcohol Dependence (Vol.266, January 2025) Article : PériodiqueBackground: Substance use disorders (SUDs) play a major role in global preventable disability and mortality. Even though they impact patients of all ages, adolescents and young adults (AYAs) are at increased risk of substance use at a later age.[...]
R. DE BEAUREPAIRE ; J. M. A. SINCLAIR ; M. HEYDTMANN ; G. ADDOLORATO ; H. J. AUBIN ; E. M. BERAHA ; F. CAPUTO ; J. D. CHICK ; P. DE LA SELLE ; N. FRANCHITTO ; J. C. GARBUTT ; P. S. HABER ; P. JAURY ; A. R. LINGFORD-HUGHES ; K. C. MORLEY ; C. A. MULLER ; L. OWENS ; A. PASTOR ; L. M. PATERSON ; F. PELISSIER ; B. ROLLAND ; A. STAFFORD ; A. THOMPSON ; W. VAN DEN BRINK ; L. LEGGIO ; R. AGABIO | 2018
Dans Frontiers in Psychiatry (Vol.9, 2018) Article : PériodiqueAlcohol use disorder (AUD) is a brain disorder associated with high rates of mortality and morbidity worldwide. Baclofen, a selective gamma-aminobutyric acid-B (GABA-B) receptor agonist, has emerged as a promising drug for AUD. The use of this d[...]