Cocaine Rapid Efficacy Screening Trials (CREST) : lessons learned

K. M. KAMPMAN ; LEIDERMAN D. ; T. HOLMES ; LOCASTRO J. ; D. A. BLOCH ; M. A. REID ; S. SHOPTAW ; M. A. MONTGOMERY ; T. M. WINHUSEN ; SOMOZA E. C. ; D. A. CIRAULO ; A. ELKASHEF ; F. VOCCI | 2005
Périodique

ENGLISH : Aims : The Cocaine Rapid Efficacy Screening Trials (CREST) were designed by the National Institute on Drug Abuse Division of Treatment Research and Development (NIDA, DT R&D) to rapidly screen a number of medications potentially usef[...]

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Nefazodone treatment of cocaine dependence with comorbid depressive symptoms

D. A. CIRAULO ; C. KNAPP ; J. ROTROSEN ; O. SARID-SEGAL ; A. M. CIRAULO ; LOCASTRO J. ; GREENBLATT D. J. ; LEIDERMAN D. | 2005
Périodique

Aims : In the current study, nefazodone, an antidepressant with dual action on serotonin and norepinephrine reuptake as well as 5-HT2A receptor antagonist effects, was studied in subjects with cocaine dependence and depressive symptoms, to deter[...]

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Retrospective analyses of pooled data from CREST I and CREST II trials for treatment of cocaine dependence

A. ELKASHEF ; T. H. HOLMES ; D. A. BLOCH ; S. SHOPTAW ; K. KAMPMAN ; M. S. REID ; SOMOZA E. ; D. CIRAULO ; J. ROTROSEN ; LEIDERMAN D. ; A. MONTGOMERY ; F. VOCCI | 2005
Périodique

ENGLISH : Aim : To analyze pooled data from the Cocaine Rapid Evaluation Screening Trial (CREST). Pooling data from these small pilot trials into four major drug classes permitted data exploration for treatment and covariate effects with incre[...]

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