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Auteur P. I. DARGAN |
Documents disponibles écrits par cet auteur (34)
Article : Périodique
Objective: 4-Methyl-5-(4-methylphenyl)-4,5-dihydrooxazol-2-amine (4,4'-dimethylaminorex (4,4'-DMAR)) is a derivative of the controlled substances aminorex and 4-methylaminorex marketed as a potential novel psychoactive substance. This paper brin[...]Article : Périodique
A. M. DINES ; D. M. WOOD ; C. YATES ; F. HEYERDAHL ; K. E. HOVDA ; I. GIRAUDON ; R. SEDEFOV ; P. I. DARGAN ; Euro-DEN Research Group |CONTEXT: Despite the potential for recreational drugs and new psychoactive substances (NPSs) to cause significant morbidity and mortality, there is limited collection of systematic data on acute drug/NPS toxicity in Europe. OBJECTIVE: To report[...]Article : Périodique
E. LIAKONI ; C. YATES ; A. M. DINES ; P. I. DARGAN ; F. HEYERDAHL ; K. E. HOVDA ; D. M. WOOD ; F. EYER ; M. E. LIECHTI ; Euro-DEN Plus Research Group |The aim of the study was to compare self-reported and analytically confirmed substance use in cases of acute recreational drug toxicity. We performed a retrospective analysis of emergency department presentations of acute recreational drug toxi[...]Article : Périodique
J. R. H. ARCHER ; S. HUDSON ; O. JACKSON ; T. YAMAMOTO ; C. LOVETT ; H. M. LEE ; S. RAO ; L. HUNTER ; P. I. DARGAN ; D. M. WOOD |Background: Analysis of anonymous pooled urine samples from street urinals has been used to demonstrate time-trends in the detection of classical recreational drugs and novel psychoactive substances (NPS). Aim: This study aimed to expand this t[...]Article : Périodique
Aim: Analysis of urine samples collected across a city centre, for the detection of novel psychoactive substances (NPS). Design: Cross-sectional study of anonymized urine samples used for the analysis of classical recreational drugs, NPS and me[...]Article : Périodique
Background: The published ambulance referral criteria (ARC) for assessing individuals with acute recreational drug toxicity in the prehospital setting consist of nine domains. The ARC recommend that an ambulance is called to transfer those with [...]Article : Périodique
Article : Périodique
F. HEYERDAHL ; K. E. HOVDA ; I. GIRAUDON ; C. B. YATES ; A. M. DINES ; R. SEDEFOV ; D. M. WOOD ; P. I. DARGAN |BACKGROUND: The number of new (novel) psychoactive substances (NPS) available in the illegal market is increasing; however, current monitoring of the drug situation in Europe focuses mainly on classical drugs of abuse, with limited emphasis on c[...]Article : Périodique
K. MOORE ; P. I. DARGAN ; D. M. WOOD ; F. MEASHAM |Background/Aims: To assess whether novel psychoactive substances (NPS) displace established club drugs, supplement them or act as drugs of initiation via a study of the relationship between mephedrone, ecstasy pills, cocaine and MDMA powder amon[...]Rapport
OEDT = EMCDDA ; I. GIRAUDON ; A. M. DINES ; N. SINGLETON ; A. NOOR ; P. I. DARGAN ; D. WOOD | Lisbon : OEDT / EMCDDA | Technical reports | 2020ENGLISH: This report presents the latest findings on drug-related hospital emergencies from a network of sentinel hospitals across Europe. Almost 24 000 emergency presentations were recorded at 32 sentinel hospitals over the first 4 years of th[...]Article : Périodique
O. MIRO ; P. I. DARGAN ; D. M. WOOD ; A. M. DINES ; C. YATES ; F. HEYERDAHL ; K. E. HOVDA ; I. GIRAUDON ; Euro-DEN Plus Research Group ; M. GALICIA |Objective: To analyse the epidemiology, clinical picture and emergency department (ED) management of a large series of patients who presented to European EDs after cocaine consumption, comparing data from powder (C-1 group) and crack (C-2 group)[...]Article : Périodique
Purpose: Ethylphenidate is a novel psychoactive substance that is an analogue of methylphenidate. This paper describes its availability, patterns of use, and acute effects. Methods: Searches of the scientific and grey literature (publicly acces[...]Article : Périodique
J. R. H. ARCHER ; F. MENDES ; S. HUDSON ; K. LAYNE ; P. I. DARGAN ; D. M. WOOD |Aims: To evaluate the long-term trends of new psychoactive substance (NPS) detection in pooled urine samples collected across a city centre. Methods: Pooled urine samples from portable stand-alone urinals were collected on a monthly basis over[...]Article : Périodique
Background: Acute recreational drug toxicity is a common cause of emergency department (ED) presentations. There is limited published information on the perception, knowledge and experiences of these patients with regards to seeking medical care[...]Article : Périodique
C. LEAPER ; A. M. DINES ; P. I. DARGAN ; C. YATES ; K. E. HOVDA ; F. HEYERDAHL ; I. GIRAUDON ; D. M. WOOD ; Euro-DEN Plus Research Group |Over the last few years, there have been increasing reports of the potential for dependence and misuse of gabapentinoids such as pregabalin. Recent data from the UK have demonstrated an increase in 'gabapentinoid' deaths from 1 death in 2009 to [...]Rapport
OEDT = EMCDDA ; A. M. DINES ; D. M. WOOD ; P. I. DARGAN | Lisbon : OEDT / EMCDDA | Risk assessments, ISSN 1725-4493 | 2014This report presents the data and findings of the risk assessment on the new psychoactive substance, 1-(1,3-benzodioxol-5-yl)-2-(pyrrolidin-1-yl)pentan-1-one (MDPV), that was conducted by the Scientific Committee of the EMCDDA. Concerns over t[...]Article : Périodique
Mephedrone (4-methylmethcathinone) is a synthetic cathinone that has been used as a recreational drug in Europe and elsewhere in the world since 2007. In addition to published scientific papers there are a number of different data sources availa[...]Article : Périodique
Context. There have been recent concerns about increasing use and accessibility of methoxetamine, a ketamine derivative. Few data are available to describe the clinical features associated with methoxetamine exposure. We report three cases that [...]Rapport
OEDT = EMCDDA ; D. M. WOOD ; P. I. DARGAN | Lisbon : OEDT / EMCDDA | Risk assessments, ISSN 1725-4493 | 2014This report presents the data and findings of the risk assessment on the new psychoactive substance, 2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone (methoxetamine), that was conducted by the Scientific Committee of the EMCDDA. Concerns over t[...]Livre
P. I. DARGAN, Éditeur scientifique ; D. M. WOOD, Éditeur scientifique | London : Academic Press - Elsevier | 2013"Novel Psychoactive Substances: Classification, Pharmacology and Toxicology" provides readers with background on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." This book[...]Article : Périodique
Since the turn of the 21st century, there has been an increase in the availability and use of novel psychoactive substances (also known as "legal highs") across Europe. Currently, there is limited information available on the potential acute tox[...]Article : Périodique
Aim: To conduct a follow-up study to assess the prevalence of use and popularity of emergent psychoactive drugs ("legal highs"), amongst London club-goers 12 months after previous surveys in the same location. Design: Four in situ surveys were [...]Article : Périodique
S. J. MOUNSEY ; P. I. DARGAN ; M. STEWART ; A. BROWN ; N. NEWTON ; D. M. WOOD |Background: There has been an increase in the availability of novel psychoactive substances (NPS) over the last decade. The 2013 US Monitoring the Future study suggested that the perceived risk of NPS use in US students was greater than for clas[...]Article : Périodique
A. M. DINES ; D. M. WOOD ; M. GALICIA ; C. M. YATES ; F. HEYERDAHL ; K. E. HOVDA ; I. GIRAUDON ; R. SEDEFOV ; P. I. DARGAN |Cannabis is the most commonly used illicit drug in Europe, and is generally regarded as having low acute toxicity. We present the findings of the first 6 months of data collection from the Euro-DEN project on presentations related to cannabis us[...]Article : Périodique
O. M. VALLERSNES ; A. M. DINES ; D. M. WOOD ; C. YATES ; F. HEYERDAHL ; K. E. HOVDA ; I. GIRAUDON ; P. I. DARGAN ; Euro-DEN Research Group |BACKGROUND: Psychosis can be associated with acute recreational drug and novel psychoactive substance (NPS) toxicity. However, there is limited data available on how common this is and which drugs are most frequently implicated. We describe a Eu[...]Article : Périodique
S. DAVIES ; D. M. WOOD ; G. SMITH ; J. BUTTON ; J. RAMSEY ; R. ARCHER ; D. W. HOLT ; P. I. DARGAN |Background: The supply of recreational drugs has changed and users increasingly buy 'legal highs' over the Internet. Use of these is common and there is a potential for significant toxicity associated with their use. Aim: To determine the conte[...]Bulletin : Périodique
Lettre du CRIPS, n°92 - Juin 2010 - Quelle prévention de l'usage de substances en milieux festifs ?
75e rencontre du CRIPS Ile-de-France (17 décembre 2009) ; S. FOURNIER ; T. CHARLOIS ; D. WOOD ; P. I. DARGAN ; R. LEVRAIN ; D. MESSAGER ; A. UGIDOS ; R. LABUTHIE | 2010Ce numéro spécial rend compte des communications et des débats de la 75e Rencontre du Crips Ile-de-France, qui a eu lieu le 17 décembre 2009 autour de la prévention de l'usage de substances en milieux festifs.Article : Périodique
D. M. WOOD ; P. O. BEAUMONT ; D. MAY ; P. I. DARGAN |Background: Use of drugs such as 3,4-methylenedioxy-N-methylamphetamine hydrochloride, gamma-hydroxybutyric acid, and cocaine at music and outdoor festivals is common. There are no published studies on drug toxicity at festival events celebratin[...]Article : Périodique
D. M. WOOD ; S. DAVIES ; M. PUCHNAREWICZ ; J. BUTTON ; R. ARCHER ; H. OVASKA ; J. RAMSEY ; T. LEE ; D. W. HOLT ; P. I. DARGAN |INTRODUCTION: Cathinone is a pharmacologically active alkaloid that can be extracted from the leaves of the khat plant (Catha edulis). There are synthetic derivatives of cathinone entering the recreational drug market, including mephedrone (4-me[...]Article : Périodique
D. M. WOOD ; A. M. DINES ; F. HEYERDAHL ; C. YATES ; I. GIRAUDON ; R. PAASMA ; K. E. HOVDA ; P. I. DARGAN |Aims: The initial management of acute recreational drug and new psychoactive substance (NPS) toxicity is often by non-specialists working in the night-time economy. The aim was as part of the European Drug Emergencies Network (Euro-DEN) project [...]Article : Périodique
C. E. WOLFE ; D. M. WOOD ; A. DINES ; B. P. WHATLEY ; C. YATES ; F. HEYERDAHL ; K. E. HOVDA ; I. GIRAUDON ; P. I. DARGAN ; Euro-DEN Plus Research Group |Seizures are a recognized and potentially serious complication of recreational drug use. This study examined a large international data set of presentations to Emergency Departments with acute recreational drug toxicity, the European Drug Emerge[...]Article : Périodique
O. MIRO ; G. BURILLO-PUTZE ; Y. SCHMID ; E. SALGADO ; M. E. LIECHTI ; A. M. DINES ; I. GIRAUDON ; F. HEYERDAHL ; K. E. HOVDA ; O. M. VALLERSNE ; F. EYER ; D. M. WOOD ; C. YATES ; P. I. DARGAN ; M. GALICIA ; Euro-DEN Plus Research Group |OBJECTIVE: To investigate whether the severity of acute recreation drug toxicity presentations to emergency departments (EDs) in Europe has changed in recent years and to uncover potential sex differences. DESIGN: We analysed presentations to 3[...]Article : Périodique
J. R. H. ARCHER ; P. I. DARGAN ; S. HUDSON ; S. DAVIES ; M. PUCHNAREWICZ ; A. T. KICMAN ; J. RAMSEY ; F. MEASHAM ; M. WOOD ; A. JOHNSTON ; D. M. WOOD |Background: The epidemiology on recreational drug use is based on self-reported user surveys. The scope of this is limited as users are often not aware of exactly what drug(s) they are using. Waste water (sewage plant) analysis has been used to [...]