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Article : Périodique
Nicotine acts on nearly every physiological system of the human body. While the actions of nicotine on the autonomic nervous system may be of interest in understanding possible deleterious long-term effects of smoking on the cardiovascular syste[...]
Article : Périodique
The stable isotope-labeled compound 3',-3'-dideuteronicotine (nicotine-d2) was used to investigate the disposition kinetics and effects of nicotine administered subcutaneously to 6 smokers. Plasma nicotine-d2 concentrations were measured for 8 h[...]
Périodique
N. L. BENOWITZ | 1990FRANÇAIS : Etude pharmacologique et pharmacocinétique de la caféine: son effet sur les divers organes et fonctions; son importance thérapeutique. Ces faits sont importants à connaître, compte tenu d'une possibilité de dépendance.
Chapitre
Présentation de la pharmacodynamique des drogues d'inhalation : pénétration par les poumons, circulation, action sur le cerveau, tolérance, dépendance (à travers l'exemple de la nicotine).
Article : Périodique
N. A. RIGOTTI ; N. L. BENOWITZ ; J. PROCHASKA ; S. LEISCHOW ; M. NIDES ; B. BLUMENSTEIN ; A. CLARKE ; D. CAIN ; C. JACOBS |Key Points: Question: Is cytisinicline an effective and safe pharmacotherapy to promote smoking cessation? Findings: In a randomized clinical trial that included 810 adults who smoked, both a 6-week and a 12-week course of a novel cytisiniclin[...]
Article : Périodique
Electronic cigarettes (e-cigarettes) are products that deliver a nicotine-containing aerosol (commonly called vapor) to users by heating a solution typically made up of propylene glycol or glycerol (glycerin), nicotine, and flavoring agents inve[...]
Article : Périodique
A. BHATNAGAR ; L. P. WHITSEL ; K. M. RIBISL ; C. BULLEN ; F. CHALOUPKA ; M. PIANO ; R. M. ROBERTSON ; T. McAULEY ; D. GOFF ; N. L. BENOWITZ |For decades, advocacy for tobacco control has been a priority of the American Heart Association (AHA). In partnership with major public health organizations, the association has made major strides in tobacco use prevention and cessation by prior[...]
Article : Périodique
Aims: We reviewed available research on the use, content and safety of electronic cigarettes (EC), and on their effects on users, to assess their potential for harm or benefit and to extract evidence that can guide future policy. Methods: Studi[...]
Article : Périodique
J. LE HOUEZEC ; R. HALLIDAY ; N. L. BENOWITZ ; E. CALLAWAY ; H. NAYLOR ; K. HERZIG |Many studies have found that cigarette smoking or nicotine improves mental functioning in abstinent smokers. An unresolved issue is whether this improvement is due primarily to a direct facilitation of performance or to relief of the impairment [...]
Article : Périodique
Cigarette smoking remains a leading cause of preventable disease and premature death in the United States and other countries. On average, 435,000 people in the United States die prematurely from smoking-related diseases each year; overall, smok[...]![Reduced nicotine content cigarettes, e-cigarettes and the cigarette end game [Editorial]](https://bdoc.ofdt.fr/thumbnail.php?type=1&id=78332)
Article : Périodique
The reduced nicotine content cigarette and the emergence of non-combusted nicotine products like e-cigarettes should be viewed not as alternatives but as complementary components of regulatory interventions that could virtually end combusted tob[...]Nouveauté
Article : Périodique
Nicotine is highly addictive and is primarily responsible for the maintenance of cigarette smoking. In 1994, Benowitz and Henningfield proposed the idea of federal regulation of the nicotine content of cigarettes such that the nicotine content o[...]
Périodique
KOSEL B. W. ; F. T. AWEEKA ; N. L. BENOWITZ ; SHADE S. B. ; J. F. HILTON ; LIZAK P. S. ; D. I. ABRAMS | 2002FRANÇAIS : Les effets métaboliques de la marijuana fumée et du dronabinol sont étudiés chez des patients infectés par le VIH qui reçoivent toutes les 8 heures soit 800 mg d'indinavir (n=38), soit 750 mg de nelfinavir (n=34). Les résultats montr[...]![The regulatory challenge of electronic cigarettes [Viewpoint]](https://bdoc.ofdt.fr/thumbnail.php?type=1&id=73170)
Article : Périodique
Electronic cigarettes (e-cigarettes or electronic nicotine delivery systems) heat a nicotine solution to generate vapor that is inhaled, without the combustion of tobacco and its toxic constituents. Use of e-cigarettes is increasing in the Unite[...]
Périodique
D. I. ABRAMS ; VIZOSO H. P. ; SHADE S. B. ; C. JAY ; M. E. KELLY ; N. L. BENOWITZ | 2007ENGLISH : Although cannabis may have potential therapeutic value, inhalation of a combustion product is an undesirable delivery system. The aim of the study was to investigate vaporization using the Volcano((R)) device as an alternative means [...]
