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Article : Périodique
R. N. ROSENTHAL ; W. LING ; P. CASADONTE ; F. VOCCI ; G. L. BAILEY ; K. KAMPMAN ; A. A. PATKAR ; S. CHAVOUSTIE ; C. BLASEY ; S. C. SIGMON ; K. L. BEEBE |Aims: To evaluate the safety and efficacy of buprenorphine implants (BI) versus placebo implants (PI) for the treatment of opioid dependence. A secondary aim compared BI to open-label sublingual buprenorphine/naloxone tablets (BNX). Design: Ran[...]
Article : Périodique
W. LING ; P. CASADONTE ; G. BIGELOW ; K. M. KAMPMAN ; A. A. PATKAR ; G. L. BAILEY ; R. N. ROSENTHAL ; K. L. BEEBE |Context: Limitations of existing pharmacological treatments for opioid dependence include low adherence, medication diversion, and emergence of withdrawal symptoms. Objective: To determine the efficacy of buprenorphine implants that provide a l[...]Périodique
A. A. PATKAR ; R. C. ALEXANDER ; A. LUNDY ; CERTA K. M. | 1999FRANÇAIS : De 1984 à 1996 plus de 1700 consultations psychiatriques de patients schizophrènes ont été étudiées ainsi que les résultats des analyses d'urine détectant les toxicomanies. La consommation de drogues illicites a significativement aug[...]Périodique
A. A. PATKAR ; R. C. STERLING ; E. GOTTHEIL ; S. P. WEINSTEIN | 1999FRANÇAIS : L'usage de drogues induit souvent des pathologies organiques. Les différences de symptômes ont été étudiées auprès de 101 alcooliques, 113 cocaïnomanes, et 107 individus dépendants aux opiacés recevant tous un traitement ambulatoire.[...]Périodique
A. A. PATKAR ; C. C. THORNTON ; P. MANNELLI ; K. P. HILL ; E. GOTTHEIL ; M. J. VERGARE ; S. P. WEINSTEIN | 2004ENGLISH : We investigated whether pretreatment characteristics and measures of outcome differed for alcohol-, cocaine-, and multisubstance-dependent patients receiving outpatient substance abuse treatment. One hundred and forty substance depen[...]Périodique
C. THORNTON ; E. GOTTHEIL ; A. A. PATKAR ; S. WEINSTEIN | 2003ENGLISH : We compared outcomes during and after treatment for mixed substance dependent patients (N=143) randomly assigned to a high-structure, behaviorally-oriented (HSB) or a low-structure, facilitative (LSF) individual counseling style. We [...]Article : Périodique
G. E. WOODY ; S. A. POOLE ; G. SUBRAMANIAM ; DUGOSH K. ; M. BOGENSCHUTZ ; P. ABBOTT ; A. A. PATKAR ; PUBLICKER M. ; MCCAIN K. ; J. SHARPE POTTER ; R. FORMAN ; VETTER V. ; L. McNICHOLAS ; J. BLAINE ; K. G. LYNCH ; P. J. FUDALA |Context: The usual treatment for opioid-addicted youth is detoxification and counseling. Extended medication-assisted therapy may be more helpful. Objective: To evaluate the efficacy of continuing buprenorphine-naloxone for 12 weeks vs detoxif[...]Périodique
C. C. THORNTON ; A. A. PATKAR ; H. W. MURRAY ; P. MANNELLI ; E. GOTTHEIL ; M. J. VERGARE ; S. P. WEINSTEIN | 2003ENGLISH : We studied whether pretreatment levels of learned helplessness (LH) were related to outcomes for substance-dependent individuals receiving high-structure, behaviorally oriented (HSB) or low-structure, facilitative (LSF) treatment. Th[...]Périodique
A. A. PATKAR ; V. BATRA ; P. MANNELI ; S. EVERS-CASEY ; M. J. VERGARE | 2005Despite the widespread use of tobacco and marijuana by cocaine abusers, it remains unclear whether combined tobacco and marijuana smoking is more harmful than tobacco smoking alone in cocaine abusers. We investigated the differences in medical s[...]Périodique
P. MANNELLI ; A. A. PATKAR ; H. W. MURRAY ; CERTA K. ; PEINDL K. ; M. MATTILA-EVENDEN ; W. H. BERRETTINI | 2005ENGLISH : The serotonin transporter (5-HTT) regulates serotonin transmission and modulates behavioral effects of drug of abuse. A polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) yielding a short (S) and long (L[...]Périodique
A. A. PATKAR ; H. W. MURRAY ; P. MANNELLI ; E. GOTTHEIL ; S. P. WEINSTEIN ; M. J. VERGARE | 2004ENGLISH : We investigated whether measures of impulsivity, aggression and sensation seeking differed between cocaine-dependent subjects and controls, and whether these measures were related to treatment-outcome for cocaine patients. Pre-treatm[...]Périodique
A. A. PATKAR ; C. C. THORNTON ; W. H. BERRETTINI ; E. GOTTHEIL ; S. P. WEINSTEIN ; K. P. HILL | 2002ENGLISH : We investigated whether urine drug screens (UDS) at admission and platelet paroxetine binding, a measure of serotonin transporter sites, were related to outcome measures for cocaine patients in treatment. Tritiated paroxetine binding[...]Périodique
A. A. PATKAR ; E. GOTTHEIL ; W. H. BERRETTINI ; K. P. HILL ; C. C. THORNTON ; S. P. WEINSTEIN | 2003We investigated whether platelet-tritiated paroxetine binding, a measure of serotonin uptake sites, and behavioral measures of impulsivity, aggression, and craving differed between cocaine-dependent subjects and controls and whether paroxetine b[...]Périodique
A. A. PATKAR ; E. GOTTHEIL ; W. H. BERRETTINI ; C. C. THORNTON ; K. P. HILL ; S. P. WEINSTEIN | 2003ENGLISH : We investigated whether platelet tritiated paroxetine binding, a measure of serotonin uptake sites differed between cocaine-dependent subjects and controls, and whether paroxetine binding was related to treatment-outcome for cocaine [...]Périodique
A. A. PATKAR ; R. C. STERLING ; F. T. LEONE ; A. LUNDY ; S. P. WEINSTEIN | 2002Despite widespread use of tobacco by alcohol and drug abusers, the medical effects of smoking remain understudied among such individuals. We investigated the relationship between tobacco smoking and medical symptoms among 87 cocaine-, 98 opiate-[...]
