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Périodique
G. GERRA ; A. ZAIMOVIC ; M. A. RAGGI ; F. GIUSTI ; R. DELSIGNORE ; S. BERTACCA ; F. BRAMBILLA | 2001ENGLISH : Objective measures of experimentally-induced aggressiveness were evaluated in 20 methadone-treated heroin addicts, in comparison to 20 normal healthy male subjects. All the subjects were submitted to preliminary DSM IV interviews, Bu[...]
Article : Périodique
Maintenance therapy with methadone or buprenorphine-based regimens reduces opioid dependence and associated harms. The perception that methadone is more effective than buprenorphine for maintenance treatment has been based on low buprenorphine d[...]
Article : Périodique
G. QUAGLIO ; C. PATTARO ; G. GERRA ; P. MEZZELANI ; L. MONTANARI ; D. C. DES JARLAIS ; F. LUGOBONI |The aim of this study was to assess the attitudes of Italian physicians regarding buprenorphine and its clinical use approximately 6 years after the medication was introduced into clinical practice. The sample consisted of 305 randomly selected [...]
Article : Périodique
Buprenorphine treatment outcome in dually diagnosed heroin dependent patients: A retrospective study
G. GERRA ; C. LEONARDI ; A. D'AMORE ; STREPPAROLA G. ; FAGETTI R. ; C. ASSI ; A. ZAIMOVIC ; LUCCHINI A. |The present study compared retrospectively in a clinical non-experimental setting the efficacy of buprenorphine (BUP) in different subgroups of dually diagnosed and non-dually diagnosed opioid-dependent patients: all the subjects included in the[...]
Périodique
G. GERRA ; BORELLA F. ; A. ZAIMOVIC ; G. MOI ; BUSSANDRI M. ; BUBICI C. ; S. BERTACCA | 2004ENGLISH : The present study compared in a clinical non-experimental setting the efficacy of buprenorphine (BUP) and methadone (METH) in the treatment of opioid dependence: all the subjects included in the study showed severe long-lasting heroi[...]
Périodique
G. GERRA ; A. MARCATO ; R. CACCAVARI ; FONTANESI B. ; R. DELSIGNORE ; G. FERTONANI ; P. AVANZINI ; RUSTICHELLI P. ; PASSERI M. | 1995FRANÇAIS : De bons résultats de désintoxication ont été obtenus en utilisant conjointement de la clonidine et des antagonistes des récepteurs d'opiacés. Une comparaison des symptômes de sevrage manifestés par 152 héroïnomanes a été effectuée ap[...]
Rapport
The aim of this draft discussion paper, "From coercion to cohesion: Treating drug dependence through healthcare, not punishment", is to promote a health-oriented approach to drug dependence. The International Drug Control Conventions give Member[...]
Article : Périodique
G. GERRA ; G. FERTONANI ; A. ZAIMOVIC ; I. ROTA-GRAZIOSI ; P. AVANZINI ; R. CACCAVARI ; R. DELSIGNORE ; LUCCHINI A. |FRANÇAIS : Les inhibiteurs de la recapture de la sérotonine peuvent être considérés comme des médicaments d'avenir pour le traitement des dépendances. Toutefois, les variations de groupes de toxicomanes montrent que la naltrexone entraine un t[...]
Périodique
P. P. VESCOVI ; PEDRAZZONI M. ; G. GERRA ; PIOLI G. ; MANINETTI L. ; MICHELINI M. ; PASSERI M. | 1989FRANÇAIS : On compare huit sujets témoins avec huit héroinomanes admis depuuis peu dans une communauté thérapeutique pour évaluer les taux d'ACTH, de beta-endorphine et de met-encéphaline plasmatiques lors d'une hyperthermie provoquée par sauna[...]
Périodique
G. GERRA ; A. ZAIMOVIC ; F. GIUSTI ; G. MOI ; C. BREWER | 2002ENGLISH : Flumazenil (FLU), a benzodiazepine (BZD) partial agonist with a weak intrinsic activity, was previously found unable to precipitate withdrawal in tolerant subjects submitted to long-lasting BZD treatment. The potential use of FLU to [...]
Périodique
G. GERRA ; A. ZAIMOVIC ; F. GIUSTI ; C. DI GENNARO ; U. ZAMBELLI ; S. GARDINI ; R. DELSIGNORE | 2001The aim of the present study is to evaluate lofexidine and clonidine, in an accelerated opiate detoxification procedure (3 days), without anaesthesia. Forty heroin-dependent individuals were detoxified, evaluating withdrawal symptoms, craving le[...]
Périodique
G. GERRA ; M. FERRI ; POLIDORI E. ; G. SANTORO ; A. ZAIMOVIC ; STERNIERI E. | 2003ENGLISH : Data were collected from 265 heroin-dependent patients in long-term methadone maintenance treatment for methadone dosage, administration method, illicit drug and problematic alcohol use, psychiatric diagnoses, quality of interpersona[...]
Article : Périodique
Naltrexone treatment has demonstrated some advantages for special populations of heroin addicted individuals, but patients' compliance seems to be very poor, with a low adherence and low retention rate. Kappa-opioid system overdrive seems to con[...]
Périodique
G. GERRA ; A. ZAIMOVIC ; G. MOI ; BUSSANDRI M. ; R. DELSIGNORE ; R. CACCAVARI ; F. BRAMBILLA | 2003ENGLISH : The function of the central alpha-adrenergic, serotoninergic and dopaminergic systems was investigated in 30 heroin-dependent subjects, 6-8 weeks after detoxification and in 22 psychophysically healthy controls (group C). Twelve hero[...]
Périodique
M. HANEY ; A. S. WARD ; G. GERRA ; R. W. FOLTIN | 2001To study the consequences of repeated smoked cocaine use on central serotonergic and dopaminergic function, the effects of d-fenfluramine (d-FEN) and bromocriptine on plasma hormones were determined at three time-points following repeated cocain[...]
