A clinical crossroads for MDMA

C. GUILLOT | 2005
Dans Journal of Psychoactive Drugs (Vol.37 n°4, 2005) Article : Périodique

ENGLISH : Clinical studies of MDMA have been hindered by the fear of harming participants through MDMA-induced neurotoxicity. However, experimental animal studies and brain imaging studies of recreational Ecstasy users have not evidenced that [...]

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Is recreational ecstasy (MDMA) use associated with higher levels of depressive symptoms ?

C. GUILLOT | 2007
Dans Journal of Psychoactive Drugs (Vol.39 n°1, 2007) Article : Périodique

ENGLISH : Due to potential serotonergic deficits, 3,4-methylenedioxymethamphetamine (MDMA or Ecstasy) may cause long-term mood disruptions in recreational Ecstasy users. The purpose of this review is to evaluate the evidence for a relationship[...]

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Recreational ecstasy use and depression

C. GUILLOT ; GREENWAY D. | 2006
Dans Journal of Psychopharmacology (Vol.20, n°3, 2006) Article : Périodique

Research in laboratory animals has shown that 3,4-methylenedioxymethamphetamine (MDMA or ecstasy) destroys serotonergic axons in the brain at certain doses. Serotonin is known to take part in the regulation of mood in humans. Many researchers ha[...]

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