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Auteur N. BERTHOLET
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2013 Update in addiction medicine for the generalist / A. J. GORDON ; N. BERTHOLET ; J. McNEELY ; J. L. STARRELS ; J. M. TETRAULT ; A. Y. WALLEY in Addiction Science and Clinical Practice, Vol.8, n°18 (November 2013)
Titre : 2013 Update in addiction medicine for the generalist Type de document : Périodique Auteurs : A. J. GORDON ; N. BERTHOLET ; J. McNEELY ; J. L. STARRELS ; J. M. TETRAULT ; A. Y. WALLEY Année de publication : 2013 Article en page(s) : 13 p. Langues : Anglais (eng) Mots-clés : Thésaurus TOXIBASE
MEDECIN GENERALISTE ; ADDICTOLOGIE ; SOINS DE PREMIER RECOURS ; ALCOOL ; PRODUIT ILLICITE ; DEPISTAGE ; INTERVENTION BREVE ; PHARMACOTHERAPIE ; EFFICACITE ; PRATIQUE PROFESSIONNELLE
Discipline : TRA Traitement et prise en charge / Treatment and care Résumé : Increasingly, patients with unhealthy alcohol and other drug use are being seen in primary care and other non-specialty addiction settings. Primary care providers are well positioned to screen, assess, and treat patients with alcohol and other drug use because this use, and substance use disorders, may contribute to a host of medical and mental health harms. We sought to identify and examine important recent advances in addiction medicine in the medical literature that have implications for the care of patients in primary care or other generalist settings. To accomplish this aim, we selected articles in the field of addiction medicine, critically appraised and summarized the manuscripts, and highlighted their implications for generalist practice. During an initial review, we identified articles through an electronic Medline search (limited to human studies and in English) using search terms for alcohol and other drugs of abuse published from January 2010 to January 2012. After this initial review, we searched for other literature in web-based or journal resources for potential articles of interest. From the list of articles identified in these initial reviews, each of the six authors independently selected articles for more intensive review and identified the ones they found to have a potential impact on generalist practice. The identified articles were then ranked by the number of authors who selected each article. Through a consensus process over 4 meetings, the authors reached agreement on the articles with implications for practice for generalist clinicians that warranted inclusion for discussion. The authors then grouped the articles into five categories: 1) screening and brief interventions in outpatient settings, 2) identification and management of substance use among inpatients, 3) medical complications of substance use, 4) use of pharmacotherapy for addiction treatment in primary care and its complications, and 5) integration of addiction treatment and medical care. The authors discuss each selected articles' merits, limitations, conclusions, and implication to advancing addiction screening, assessment, and treatment of addiction in generalist physician practice environments. Domaine : Alcool / Alcohol ; Drogues illicites / Illicit drugs Sous-type de document : Revue de la littérature / Literature review Refs biblio. : 73 Affiliation : VA Pittsburgh Healthcare System and University of Pittsburgh, Pittsburgh, PA, USA Lien : http://dx.doi.org/10.1186/1940-0640-8-18 Permalink :
in Addiction Science and Clinical Practice > Vol.8, n°18 (November 2013) . - 13 p.[article]Brief alcohol intervention as pragmatic intervention: Who is voluntarily taking an offered intervention? / G. GMEL ; J. GAUME ; N. BERTHOLET ; J. B. DAEPPEN in Alcohol, Vol.46, n°6 (September 2012)
Titre : Brief alcohol intervention as pragmatic intervention: Who is voluntarily taking an offered intervention? Type de document : Périodique Auteurs : G. GMEL ; J. GAUME ; N. BERTHOLET ; J. B. DAEPPEN Année de publication : 2012 Article en page(s) : 551-558 Langues : Anglais (eng) Mots-clés : Thésaurus Géographique
ALCOOL ; INTERVENTION BREVE ; ADULTE JEUNE ; EFFICACITE ; SEXE MASCULIN ; ABUS ; DEPISTAGE
Discipline : TRA Traitement et prise en charge / Treatment and care Résumé : Brief alcohol interventions (BAI) have shown the potential to decrease problematic alcohol use among adolescents and young adults. Most of the BAI studies have been efficacy trials designed to achieve high internal validity but have raised questions regarding the feasibility of large-scale implementation. Providing interventions for those voluntarily wanting them might offer an alternative, and studies using this design would be more similar to effectiveness studies. The present research compares randomly selected 20-year-old men who took part in a scientific trial (efficacy) with those who voluntarily sought an intervention (effectiveness). Sampling took place during army recruitment procedures that are mandatory for all males in Switzerland. At-risk drinking (20+ drinks per week, or more than one risky drinking occasion of 6+ drinks per month) was determined a posteriori; there was no screening. There were a higher percentage of at-risk drinkers in the volunteer arm at baseline, but at-risk drinkers did not differ from those in the trial arm on any of the assessed alcohol measures. This suggests that offering BAI on a large-scale, voluntary basis may reach at-risk drinkers as effectively as do more scientifically oriented trials, without needing to adhere to screening and stringent research procedures. Nevertheless, BAI was more effective for at-risk drinkers who were invited for trial participation versus those who volunteered. This could be due to behavior that is already consolidated and is difficult to change. Lacking further modifications, real-world implementations of BAI for young men may be less effective than randomized controlled trials designed to test the efficacy of BAI. Domaine : Alcool / Alcohol Affiliation : Alcohol Treatment Centre, Lausanne University Hospital CHUV, Lausanne, Switzerland Permalink :
in Alcohol > Vol.46, n°6 (September 2012) . - 551-558[article]Effectiveness of brief alcohol interventions in primary care populations [Review] / E. F. S. KANER ; F. R. BEYER ; C. MUIRHEAD ; F. CAMPBELL ; E. D. PIENAAR ; N. BERTHOLET ; J. B. DAEPPEN ; J. B. SAUNDERS ; B. BURNAND in Cochrane Database of Systematic Reviews, n°2 (2018)
Titre : Effectiveness of brief alcohol interventions in primary care populations [Review] Type de document : Périodique Auteurs : E. F. S. KANER ; F. R. BEYER ; C. MUIRHEAD ; F. CAMPBELL ; E. D. PIENAAR ; N. BERTHOLET ; J. B. DAEPPEN ; J. B. SAUNDERS ; B. BURNAND Année de publication : 2018 Article en page(s) : CD004148 ; 252 p. Langues : Anglais (eng) Mots-clés : Thésaurus TOXIBASE
INTERVENTION BREVE ; ALCOOL ; EFFICACITE ; REPERAGE PRECOCE ; MEDECIN GENERALISTE ; URGENCE ; SOINS DE PREMIER RECOURS ; USAGE PROBLEMATIQUE ; INTERVENTION
Discipline : TRA Traitement et prise en charge / Treatment and care Résumé : What is the aim of this review?
We aimed to find out whether brief interventions with doctors and nurses in general practices or emergency care can reduce heavy drinking. We assessed the findings from 69 trials that involved a total of 33,642 participants; of these 34 studies (15,197 participants) provided data for the main analysis.
Brief interventions in primary care settings aim to reduce heavy drinking compared to people who received usual care or brief written information. Longer interventions probably make little or no difference to heavy drinking compared to brief intervention.
What was studied in the review?
One way to reduce heavy drinking may be for doctors and nurses to provide brief advice or brief counselling to targeted people who consult general practitioners or other primary health care providers. People seeking primary healthcare are routinely asked about their drinking behaviour because alcohol use can affect many health conditions.
Brief interventions typically include feedback on alcohol use and health-related harms, identification of high risk situations for heavy drinking, simple advice about how to cut down drinking, strategies that can increase motivation to change drinking behaviour, and the development of a personal plan to reduce drinking. Brief interventions are designed to be delivered in regular consultations, which are often 5 to 15 minutes with doctors and around 20 to 30 minutes with nurses. Although short in duration, brief interventions can be delivered in one to five sessions. We did not include digital interventions in this review.
Search date: The evidence is current to September 2017.
Study funding: Funding sources were reported by 60 (87%) studies. Of these, 58 studies were funded by government institutes, research bodies or charitable foundations. One study was partly funded by a pharmaceutical company and a brewers association, another by a company developing diagnostic testing equipment. Nine studies did not report study funding sources.
What are the main results of the review?
We included 69 controlled trials conducted in many countries. Most studies were conducted in general practice and emergency care. Study participants received brief intervention or usual care or written information about alcohol (control group).
The amount of alcohol people drank each week was reported by 34 trials (15,197 participants) at one-year follow-up and showed that people who received the brief intervention drank less than control group participants (moderate-quality evidence). The reduction was around a pint of beer (475 mL) or a third of a bottle of wine (250 mL) less each week.
Longer counselling probably provided little additional benefit compared to brief intervention or no intervention.
One trial reported that the intervention adversely affected binge drinking for women, and two reported that no adverse effects resulted from receiving brief interventions. Most studies did not mention adverse effects.
Quality of the evidence:
Findings may have been affected because participants and practitioners were often aware that brief interventions focused on alcohol. Furthermore, some participants could not be contacted at one-year follow-up to report drinking levels. Overall, evidence was assessed as mostly moderate-quality. This means the reported effect size and direction is likely to be close to the true effect of these interventions.
Domaine : Alcool / Alcohol Sous-type de document : Revue de la littérature / Literature review Affiliation : Institute of Health and Society, Newcastle University, Richardson Road, Newcastle upon Tyne, UK Permalink :
in Cochrane Database of Systematic Reviews > n°2 (2018) . - CD004148 ; 252 p.[article]Efficacy of brief motivational intervention in reducing binge drinking in young men: A randomized controlled trial / J. B. DAEPPEN ; N. BERTHOLET ; J. GAUME ; C. FORTINI ; M. FAOUZI ; G. GMEL in Drug and Alcohol Dependence, Vol.113, n°1 (January 2011)
Titre : Efficacy of brief motivational intervention in reducing binge drinking in young men: A randomized controlled trial Type de document : Périodique Auteurs : J. B. DAEPPEN ; N. BERTHOLET ; J. GAUME ; C. FORTINI ; M. FAOUZI ; G. GMEL Année de publication : 2011 Article en page(s) : 69-75 Langues : Anglais (eng) Mots-clés : Thésaurus TOXIBASE
ALCOOL ; INTERVENTION BREVE ; JEUNE ; SEXE MASCULIN ; ARMEE ; ETUDE RANDOMISEE ; ABUS ; REDUCTION DE CONSOMMATION ; MOTIVATION ; EFFICACITE
Discipline : TRA Traitement et prise en charge / Treatment and care Résumé : Background: Brief motivational intervention (BMI) is one of the few effective strategies targeting alcohol consumption, but has not been tested in young men in the community. We evaluated the efficacy of BMI in reducing alcohol use and related problems among binge drinkers and in maintaining low-risk drinking among non-bingers.
Methods: A random sample of a census of men included during army conscription (which is mandatory for 20-year-old males in Switzerland) was randomized to receive a single face-to-face BMI session (N = 199) or no intervention (N = 219). A six-month follow-up rate was obtained for 88.7% of the subjects.
Results: Among binge drinkers, there was 20% less drinking in the BMI group versus the control group (incidence rate ratio = 0.80, confidence interval 0.66-0.98, p = 0.03); the BMI group showed a weekly reduction of 1.5 drinks compared to an increase of 0.8 drinks weekly in the control group. Among subjects who experienced one or more alcohol-related consequences over the last 12 months, there was 19% less drinking in the BMI group compared to the control group (incidence rate ratio = 0.81, confidence interval 0.67-0.97, p = 0.04). Among non-bingers, BMI did not contribute to the maintenance of low-risk drinking.
Conclusion: BMI reduced the alcohol use of binge drinkers, particularly among those who experienced certain alcohol-related adverse consequences. No preventive effect of BMI was observed among non-bingers. BMI is a plausible secondary preventive option for young binge drinkers. [Author's abstract]
Domaine : Alcool / Alcohol Affiliation : Alcohol Treatment Centre, Lausanne University Hospital, Mont-Paisible 16, 1011 Lausanne, Switzerland / Suisse Permalink :
in Drug and Alcohol Dependence > Vol.113, n°1 (January 2011) . - 69-75[article]Internet-based brief intervention for young men with unhealthy alcohol use: a randomized controlled trial in a general population sample / N. BERTHOLET ; J. A. CUNNINGHAM ; M. FAOUZI ; J. GAUME ; G. GMEL ; B. BURNAND ; J. B. DAEPPEN in Addiction, Vol.110, n°11 (November 2015)
Titre : Internet-based brief intervention for young men with unhealthy alcohol use: a randomized controlled trial in a general population sample Type de document : Périodique Auteurs : N. BERTHOLET ; J. A. CUNNINGHAM ; M. FAOUZI ; J. GAUME ; G. GMEL ; B. BURNAND ; J. B. DAEPPEN Année de publication : 2015 Article en page(s) : 1735-1743 Note générale : Commentary: Proceed, with caution. Patton R., p. 1744-1745. Langues : Anglais (eng) Mots-clés : Thésaurus Géographique
INTERVENTION BREVE ; ALCOOL ; INTERNET ; ETUDE RANDOMISEE ; POPULATION GENERALE ; SEXE MASCULIN ; JEUNE ; USAGE PROBLEMATIQUE ; AUDIT ; REDUCTION DE CONSOMMATION
Discipline : PRE Prévention / Prevention Résumé : Aim: To test the efficacy of an internet-based brief intervention (IBI) in decreasing alcohol use among young Swiss men aged 21 years on average.
Design: Two parallel-group randomized controlled trial with a 1 : 1 allocation ratio containing follow-up assessments at 1 and 6 months post-randomization.
Setting: Internet-based study in a general population sample.
Participants: Twenty-one-year-old men from Switzerland with unhealthy alcohol use (> 14 drinks/week or >= 6 drinks/occasion at least monthly or Alcohol Use Disorders Identification Test (AUDIT) scores >= 8) Intervention IBI consisting of (1) normative feedback, (2) feedback on consequences of alcohol use, (3) calorific value of reported consumption, (4) computed blood alcohol concentration for reported consumption, (5) indication of risk, (6) information on alcohol and health and (7) recommendations indicating low-risk drinking limits. Control condition: no intervention (assessment only).
Measurements: At 1 and 6 months: quantity/frequency questions on alcohol use (primary outcome: number of drinks/week) and binge drinking prevalence; at 6 months: AUDIT score, consequences of drinking (range = 0-12).
Findings: Follow-up rates were 92% at 1 month and 91% at 6 months. At 6 months, participants in the intervention group (n = 367) reported greater reductions in the number of drinks/week than participants in the control group (n = 370) [treatment × time interaction, incidence rate ratio (RR) = 0.86, 95% confidence interval (CI) = 0.78; 0.96], but no significant differences were observed on binge drinking prevalence. There was a favourable intervention effect on AUDIT scores (IRR = 0.93, 95% CI = 0.88; 0.98), but not on the number of consequences (IRR = 0.93, 95% CI = 0.84; 1.03).
Conclusions: An internet-based brief intervention directed at harmful alcohol use among young men led to a reduction in self-reported alcohol consumption and AUDIT scores compared with a no-intervention control condition (assessment only).
Domaine : Alcool / Alcohol Refs biblio. : 38 Affiliation : Alcohol Treatment Center, Department of Community Medicine and Health, Lausanne University Hospital, Lausanne, Switzerland Cote : Abonnement Permalink :
in Addiction > Vol.110, n°11 (November 2015) . - 1735-1743[article]Is brief motivational intervention effective in reducing alcohol use among young men voluntarily receiving it? A randomized controlled trial / J. GAUME ; G. GMEL ; M. FAOUZI ; N. BERTHOLET ; J. B. DAEPPEN in Alcoholism: Clinical and Experimental Research, Vol.35, n°10 (October 2011)PermalinkNeed for informed consent in substance use studies-harm of bias? / J. STUDER ; M. MOHLER-KUO ; P. DERMOTA ; J. GAUME ; N. BERTHOLET ; C. EIDENBENZ ; J. B. DAEPPEN ; G. GMEL in Journal of Studies on Alcohol and Drugs, Vol.74, n°6 (December 2013)PermalinkPerception of the amount of drinking by others in a sample of 20-year-old men: the more I think you drink, the more I drink / N. BERTHOLET ; J. GAUME ; M. FAOUZI ; J. B. DAEPPEN ; G. GMEL in Alcohol and Alcoholism, Vol.46, n°1 (January-February 2011)PermalinkReduction of alcohol consumption by brief alcohol intervention in primary care. Systematic review and meta-analysis / N. BERTHOLETPermalinkReduction of alcohol consumption by brief alcohol intervention in primary care: systematic review and meta-analysis / N. BERTHOLET ; J. B. DAEPPEN ; V. WIETLISBACH ; M. FLEMING ; B. BURNAND in Archives of Internal Medicine, Vol.165, n°9 (May 2005)PermalinkSocioeconomic status and substance use among Swiss young men: a population-based cross-sectional study / E. CHARITONIDI ; J. STUDER ; J. GAUME ; G. GMEL ; J. B. DAEPPEN ; N. BERTHOLET in BMC Public Health, Vol.16, n°333 (2016)Permalink