Comorbid major depressive disorder as a prognostic factor in cocaine-abusing buprenorphine-maintained patients treated with desipramine and contingency management

G. GONZALEZ ; FEINGOLD A. ; A. OLIVETO ; GONSAI K. ; T. R. KOSTEN | 2003
Périodique

ENGLISH : Depression is common among patients who abuse both opiates and cocaine, and its treatment has had mixed success. This study compares buprenorphine-maintained patients with lifetime major depressive disorder (MDD, N = 53) with those n[...]

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Desipramine treatment for cocaine dependence in buprenorphine- or methadone-treated patients: Baseline urine results as predictor of response

T. KOSTEN ; M. SOFUOGLU ; J. POLING ; GONSAI K. ; A. OLIVETO | 2005
Périodique

ENGLISH : The prognostic importance of baseline urines for cocaine was examined in a randomized, placebo-controlled, twelve-week clinical trial in 165 opioid- and cocaine-dependent patients who were treated with desipramine (DMI) in combinatio[...]

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Ketoconazole increases cocaine and opioid use in methadone maintained patients

T. R. KOSTEN ; A. OLIVETO ; SEVARINO K. A. ; GONSAI K. ; FEINGOLD A. | 2002
Périodique

ENGLISH : Stress plays an important role in substance abuse problems. For example, in studies with rodents stress induces reinstatement of opioid and cocaine self-administration. In addition, attenuation of the stress response by pharmacologic[...]

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Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients: results of a randomized pilot study

G. GONZALES ; SEVARINO K. ; M. SOFUOGLU ; J. POLING ; A. OLIVETO ; GONSAI K. ; T. P. GEORGE ; T. R. KOSTEN | 2003
Périodique

FRANÇAIS : La tigabine, substance GABAérgique, diminue l'auto-administration de la cocaïne. Son efficacité et son absence de nocivité sont évaluées chez 45 cocaïnomanes en traitement de maintenance à la méthadone. A une posologie de 24mg/jour, [...]

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