Auteur K. P. GOLAY

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Cytochrome P4503A4 metabolic activity, methadone blood concentrations, and methadone doses

M. SHINDERMAN ; S. MAXWELL ; BRAWAND-AMEY M. ; K. P. GOLAY ; P. BAUMANN ; EAP C. B. | 2003
Périodique

ENGLISH : We examined in vivo the influence of cytochrome P4503A4 (CYP3A4) activity, measured by the 30 min plasma 1'OH-midazolam/ midazolam ratio after oral administration of 7.5 mg midazolam, on the methadone steady-state trough plasma conce[...]

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Increase of oral methadone dose in methadone injecting patients: a pilot study

EAP C. B. ; FELDER C. ; K. P. GOLAY ; C. UEHLINGER | 2003
Périodique

ENGLISH : A pilot study was initiated in seven methadone injecting patients to examine whether intravenous methadone use in patients in oral methadone maintenance treatment could be decreased by increased oral methadone dose. During the study,[...]

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