Historique
Article de Périodique
Recreational nitrous oxide dosing and administration and its use in traffic: An online survey (2025)
Auteur(s) :
VINCKENBOSCH, F. ;
THEUNISSEN, E. ;
STELLING, A. ;
GOLDENBELD, C. ;
RAMAEKERS, J. G.
Année
2025
Page(s) :
495-511
Langue(s) :
Anglais
Domaine :
Autres substances / Other substances
Discipline :
EPI (Epidémiologie / Epidemiology)
Thésaurus géographique
PAYS-BAS
Thésaurus mots-clés
PROTOXYDE D'AZOTE
;
USAGE RECREATIF
;
CONDUITE DE VEHICULE
;
SECURITE ROUTIERE
;
ETUDE TRANSVERSALE
;
CONSOMMATION
;
VOIE D'ADMINISTRATION
;
INHALATION
;
INHALANTS
;
PREVALENCE
Résumé :
Nitrous oxide (N2O) is a popular recreational intoxicant and associated paraphernalia are increasingly being found at road traffic accident scenes in the Netherlands, suggesting that N2O intoxication causally contributes to the occurrence of a significant number of road traffic accidents. However, information on the pharmacodynamics- and kinetic characteristics of recreational N2O use is limited, impeding policy making and enforcement. This investigation aimed to determine a representative dosing method for recreational N2O use and establish a relevant timeframe for assessing psychomotoric functioning in future research. Online survey responses of 511 N2O users revealed that the majority inhaled N2O from party balloons filled with 4-14 L of N2O. Inhalation typically involved a repetitive "rebreathing" technique with 20-30 second breaks every six cycles, or without breaks, for approximately 12 cycles in total. 10.3% of respondents admitted to have inhaled N2O during driving in the past. Driving departure within 1 hour of inhalation was common, providing a relevant timeframe for the investigation of psychomotoric effects of recreational N2O use in future research. [Author's abstract]
Affiliation :
Department of Neuropsychology and Psychophamacology, Maastricht University, Maastricht, The Netherlands
Vias Institute, Brussels, Belgium
Vias Institute, Brussels, Belgium