Historique
Article de Périodique
A narrative review on alcohol use in women: insight into the telescoping hypothesis from a biopsychosocial perspective (2025)
Auteur(s) :
KIRSCH, D. E. ;
BELNAP, M. A. ;
KADY, A. ;
RAY, L. A.
Année
2025
Page(s) :
14-30
Sous-type de document :
Revue de la littérature / Literature review
Langue(s) :
Anglais
Refs biblio. :
212
Domaine :
Alcool / Alcohol
Discipline :
SAN (Santé publique / Public health)
Thésaurus mots-clés
SEXE FEMININ
;
ALCOOL
;
PSYCHOSOCIOLOGIE
;
BIOLOGIE
;
FACTEUR DE RISQUE
;
DIFFERENCE DE GENRE
;
AFFECT
;
STRESS
;
PHARMACOLOGIE
;
NEUROBIOLOGIE
;
ENDOCRINOLOGIE
;
PSYCHOPATHOLOGIE
;
SENSIBILITE
;
SANTE
;
PATHOLOGIE ORGANIQUE
Résumé :
Background: There has been a dramatic rise in alcohol consumption and alcohol use disorder (AUD) among women. Recently, the field has made substantial progress toward better understanding sex and gender differences in AUD. This research has suggested accelerated progression to AUD and associated health consequences in women, a phenomenon referred to as "telescoping."
Objective: To examine evidence for the telescoping hypothesis from a biopsychosocial perspective.
Methods: This narrative review examined and integrated research on biological, psychological, and socio-environmental factors that may contribute to the development and progression of AUD in women.
Results: Biopsychosocial research has revealed sex- and gender-specific risk factors and pathways to AUD onset and progression. Biological sex differences render females more vulnerable to alcohol-related toxicity across various biological systems, including the brain. Notably, sex and gender differences are consistently observed in the neural circuitry underlying emotional and stress regulation, and are hypothesized to increase risk for an internalizing pathway to AUD in women. Psychological research indicates women experience greater negative emotionality and are more likely to use alcohol as a means to alleviate negative emotions compared with men. Socio-environmental factors, such as familial and peer isolation, appear to interact with biological and psychological processes in a way that increases risk for negative emotionality and associated alcohol use in women.
Conclusion: There appears to be a complex interplay of biopsychosocial factors that increase risk for AUD onset and progression in women through an internalizing pathway. Developing targeted interventions for women with AUD that specifically target internalizing processes is critical. [Author's abstract]
Objective: To examine evidence for the telescoping hypothesis from a biopsychosocial perspective.
Methods: This narrative review examined and integrated research on biological, psychological, and socio-environmental factors that may contribute to the development and progression of AUD in women.
Results: Biopsychosocial research has revealed sex- and gender-specific risk factors and pathways to AUD onset and progression. Biological sex differences render females more vulnerable to alcohol-related toxicity across various biological systems, including the brain. Notably, sex and gender differences are consistently observed in the neural circuitry underlying emotional and stress regulation, and are hypothesized to increase risk for an internalizing pathway to AUD in women. Psychological research indicates women experience greater negative emotionality and are more likely to use alcohol as a means to alleviate negative emotions compared with men. Socio-environmental factors, such as familial and peer isolation, appear to interact with biological and psychological processes in a way that increases risk for negative emotionality and associated alcohol use in women.
Conclusion: There appears to be a complex interplay of biopsychosocial factors that increase risk for AUD onset and progression in women through an internalizing pathway. Developing targeted interventions for women with AUD that specifically target internalizing processes is critical. [Author's abstract]
Affiliation :
Department of Psychology, University of California, Los Angeles, CA, USA.
Neuroscience Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, USA.
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, USA.
Neuroscience Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, USA.
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, USA.