Historique
Article de Périodique
Identification of N-pyrrolidino protonitazene in powders sold as heroin and associated with overdose clusters in Dublin and Cork, Ireland (2025)
Auteur(s) :
KILLORAN, S. ;
McNAMARA, S. ;
KAVANAGH, P. ;
O'BRIEN, J. ;
LAKES, R.
Année
2025
Page(s) :
350-357
Langue(s) :
Anglais
Refs biblio. :
20
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus géographique
IRLANDE
Thésaurus mots-clés
NITAZENES
;
HEROINE
;
SURDOSE
;
DROGUES DE SYNTHESE
;
OPIOIDES
;
TOXICOLOGIE
;
ANALYSE CHIMIQUE
Résumé :
Synthetic opioids have been associated globally with adverse effects in drug users. The nitazene group of drugs is a relatively new addition to the synthetic opioid class emerging in Europe in 2019. Some nitazenes have been shown to be more potent than fentanyl. Overdose clusters in heroin users in Dublin (57 cases) and Cork (20 cases), Ireland, in November and December 2023, respectively, prompted a rapid response from a number of Irish laboratories to identify the substance(s) of concern. Light brown (tan) powders were obtained from cases associated with overdoses, and the results from these analyses by collaboration of four laboratories are reported here. The samples were found to contain N-pyrrolidino protonitazene (protonitazepyne), caffeine, paracetamol, benzoic acid and mannitol. [Author's abstract]
Affiliation :
HSE National Drug Treatment Centre Laboratory, Dublin, Ireland