Historique
Article de Périodique
High lifetime prevalence of regular nitrous oxide use in French medical students (2024)
Auteur(s) :
THEVENIN, M. ;
MALMARTEL, A. ;
KARILA, L. ;
CAMUS JACQMIN, M.
Année
2024
Page(s) :
682-689
Langue(s) :
Anglais
Refs biblio. :
22
Domaine :
Drogues illicites / Illicit drugs
Discipline :
EPI (Epidémiologie / Epidemiology)
Thésaurus géographique
FRANCE
;
ILE-DE-FRANCE
Thésaurus mots-clés
MILIEU ETUDIANT
;
MEDECINE
;
JEUNE ADULTE
;
PROTOXYDE D'AZOTE
;
PREVALENCE
;
ETUDE TRANSVERSALE
;
USAGE RECREATIF
;
EFFET SECONDAIRE
Résumé :
Background: Although nitrous oxide (N2O) is increasingly misused recreationally, its use and risks among medical students who have professional access to it are rarely explored.
Objectives: To investigate the recreational use of N2O among medical students in Paris Region (France).
Methods: This cross-sectional study used an online questionnaire distributed in 2022 through social networks, to all medical students (undergraduate student from the 2nd year of medical studies to residents until the end of the residency) from the six medical universities in Paris Region. We collected demographic characteristics, patterns of N2O consumption, co-consumptions, and N2O training (academic course or self-training). Factors associated with N2O consumption and complications were analyzed using multivariable logistic regressions.
Results: The questionnaires of 444 students (mean age: 25.9 years (SD = 2.69), 75.5% female, and 63.74% residents) were analyzed. Recreational N2O consumption was reported by 71.85% of students and 20.50% consumed at least monthly. N2O consumption was associated with being a resident (versus undergraduate student) (adjusted OR (aOR) = 3.07[1.45-6.72]; p < .01), receiving training on N2O (aOR) = 3.13[1.84-6.24]; p < .01), and consumption of cannabis (aOR = 18.21[3.47-104.26]; p < .01), ecstasy (aOR = NA, p = .048) and poppers (aOR = 13.9[2.64-77.94]; p < .01). Complications (mainly dizziness, paresthesia and burns) were reported in 8.15% of students consuming N2O. They were associated with consuming more than 10 balloons per intake (aOR = 6.04[1.32-25.00]; p < .01) and inversely associated with receiving training (aOR = 0.35[0.14-0.86]; p = .01).
Conclusions: Almost three-quarters of medical students experienced recreational N2O consumption, particularly with poly-drug use. Given that complications were associated with high consumption and lack of education, risk training and screening for N2O consumption could be beneficial. [Author's abstract]
Objectives: To investigate the recreational use of N2O among medical students in Paris Region (France).
Methods: This cross-sectional study used an online questionnaire distributed in 2022 through social networks, to all medical students (undergraduate student from the 2nd year of medical studies to residents until the end of the residency) from the six medical universities in Paris Region. We collected demographic characteristics, patterns of N2O consumption, co-consumptions, and N2O training (academic course or self-training). Factors associated with N2O consumption and complications were analyzed using multivariable logistic regressions.
Results: The questionnaires of 444 students (mean age: 25.9 years (SD = 2.69), 75.5% female, and 63.74% residents) were analyzed. Recreational N2O consumption was reported by 71.85% of students and 20.50% consumed at least monthly. N2O consumption was associated with being a resident (versus undergraduate student) (adjusted OR (aOR) = 3.07[1.45-6.72]; p < .01), receiving training on N2O (aOR) = 3.13[1.84-6.24]; p < .01), and consumption of cannabis (aOR = 18.21[3.47-104.26]; p < .01), ecstasy (aOR = NA, p = .048) and poppers (aOR = 13.9[2.64-77.94]; p < .01). Complications (mainly dizziness, paresthesia and burns) were reported in 8.15% of students consuming N2O. They were associated with consuming more than 10 balloons per intake (aOR = 6.04[1.32-25.00]; p < .01) and inversely associated with receiving training (aOR = 0.35[0.14-0.86]; p = .01).
Conclusions: Almost three-quarters of medical students experienced recreational N2O consumption, particularly with poly-drug use. Given that complications were associated with high consumption and lack of education, risk training and screening for N2O consumption could be beneficial. [Author's abstract]
Affiliation :
Département de médecine générale, Université Paris Cité, Paris, France.
METHODS Team, CRESS, INSERM, INRA, Université Paris Cité, Paris, France.
Centre d'enseignement, de recherche et de traitement des addictions, Hôpital universitaire Paul-Brousse (AP-HP), Université Paris-Saclay, Villejuif, France.
Département de Neurologie, Centre Hospitalier de Melun, Melun, France.
METHODS Team, CRESS, INSERM, INRA, Université Paris Cité, Paris, France.
Centre d'enseignement, de recherche et de traitement des addictions, Hôpital universitaire Paul-Brousse (AP-HP), Université Paris-Saclay, Villejuif, France.
Département de Neurologie, Centre Hospitalier de Melun, Melun, France.