Historique
Article de Périodique
THC-O-acetate: Scarce evidence for a psychedelic cannabinoid (2024)
Auteur(s) :
KRUGER, D. J. ;
BONE, C. C. ;
MEACHAM, M. C. ;
KLEIN, C. ;
KRUGER, J. S.
Année
2024
Page(s) :
563-567
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus géographique
ETATS-UNIS
Thésaurus mots-clés
CANNABINOIDES
;
DROGUES DE SYNTHESE
;
HALLUCINATION
;
ETUDE TRANSVERSALE
;
EFFET SECONDAIRE
;
QUESTIONNAIRE
Résumé :
There is a growing interest in semi-synthetic cannabinoids, including THC-O-acetate (THC-Oac). Some cannabis marketers and users have claimed that THC-Oac produces psychedelic effects; the current study is the first to examine this claim. Researchers developed an online survey for THC-Oac consumers based on previous cannabis and psychedelic use surveys and in consultation with the moderator of an online forum. The survey assessed the experiential profile of THC-Oac and included items from the Mystical Experience Questionnaire (MEQ), an instrument for assessing psychedelic experiences. Participants reported a low to moderate level of cognitive distortions (altered sense of time, difficulties concentrating, difficulties with short-term memory) and few visuals or hallucinations. Participants' responses were significantly below the threshold for a complete mystical experience on all four MEQ dimensions. Participants who had used classic (5-HT(2A) agonist) psychedelics had lower scores on all MEQ dimensions. When asked directly, 79% responded that using THC-Oac is "not at all" or "a little" of a psychedelic experience. Some reports of psychedelic experiences may be due to expectations or contaminants. Those having prior experience with classic psychedelics had lower ratings of mystical experiences. [Author's abstract]
Affiliation :
Population Studies Center, University of Michigan, Ann Arbor, MI, USA.
Department of Community Health and Health Behavior, University at Buffalo, Buffalo, New York, USA.
Anthropology Department, Portland State University, Portland, OR, USA.
Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California San Francisco, San Francisco, CA, USA.
Department of Community Health and Health Behavior, University at Buffalo, Buffalo, New York, USA.
Anthropology Department, Portland State University, Portland, OR, USA.
Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California San Francisco, San Francisco, CA, USA.
Cote :
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