Historique
Article de Périodique
Drug checking use and interest among people who inject drugs in Toronto, Canada (2022)
Auteur(s) :
RAMMOHAN, I. ;
BOUCK, Z. ;
FUSIGBOYE, S. ;
BOWLES, J. ;
McDONALD, K. ;
MAGHSOUDI, N. ;
SCHEIM, A. ;
WERB, D.
Année
2022
Page(s) :
art. 103781
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Thésaurus géographique
CANADA
Thésaurus mots-clés
PRODUIT ILLICITE
;
INJECTION
;
TEST
;
REDUCTION DES RISQUES ET DES DOMMAGES
;
OPIOIDES
;
FENTANYL
;
SALLE DE CONSOMMATION A MOINDRE RISQUE
;
USAGER
;
ETUDE TRANSVERSALE
Résumé :
Background: Drug checking services (DCS) provide information on drug composition to inform consumption practices and monitor unregulated drug markets. We sought to identify correlates of recent informal DCS use (e.g., fentanyl test strips) and willingness to use a formal DCS (co-located within a supervised consumption site and employing laboratory-based analyses) in Toronto, Canada prior to its implementation.
Methods: We calculated outcome prevalence based on baseline questionnaire data from a cohort of people who inject drugs in downtown Toronto between November 2018-October 2019 and conducted multivariable Poisson regression analyses. Outcomes included recent (i.e., past six-month) informal DCS use and willingness to use a formal DCS, if implemented. We also conducted a sub-analysis assessing willingness to use a formal DCS following an unexpected drug reaction.
Results: Among 604 participants, 12% (n=74) reported recent informal DCS use, 73% (n=442) reported willingness to use a formal DCS, and 88% (n=530) reported willingness to use a formal DCS in response to an unexpected drug reaction. Based on 567 participants with complete data, we found that recent injection at a supervised consumption site or overdose prevention site were both associated with recent informal DCS use (respectively, adjusted prevalence ratio [aPR]=2.44, 95% confidence interval [CI]: 1.11-5.35; aPR=1.78, 95% CI: 1.00-3.15). Recent informal DCS use and recent overdose were both associated with willingness to use a formal DCS (respectively, aPR=1.15, 95% CI: 1.02-1.30; aPR=1.10, 95% CI: 1.00-1.22).
Conclusion: Although recent informal DCS use was infrequently reported in our study, willingness to use a formal DCS was high. Our findings indicate a potential role for laboratory-based DCS in mitigating overdose risk among individuals accessing the unregulated drug supply. However, barriers that impede service access or reduce interest should be addressed to ensure equitable use among those at heightened risk of overdose.
Highlights:
• Recent informal drug checking (e.g., fentanyl test strip) was infrequently reported.
• Willingness to use formal (i.e., laboratory-based) drug checking was high.
• Recent informal drug checking was associated with willingness to use formal drug checking.
• Barriers impeding service access must be addressed to ensure equitable use.
Methods: We calculated outcome prevalence based on baseline questionnaire data from a cohort of people who inject drugs in downtown Toronto between November 2018-October 2019 and conducted multivariable Poisson regression analyses. Outcomes included recent (i.e., past six-month) informal DCS use and willingness to use a formal DCS, if implemented. We also conducted a sub-analysis assessing willingness to use a formal DCS following an unexpected drug reaction.
Results: Among 604 participants, 12% (n=74) reported recent informal DCS use, 73% (n=442) reported willingness to use a formal DCS, and 88% (n=530) reported willingness to use a formal DCS in response to an unexpected drug reaction. Based on 567 participants with complete data, we found that recent injection at a supervised consumption site or overdose prevention site were both associated with recent informal DCS use (respectively, adjusted prevalence ratio [aPR]=2.44, 95% confidence interval [CI]: 1.11-5.35; aPR=1.78, 95% CI: 1.00-3.15). Recent informal DCS use and recent overdose were both associated with willingness to use a formal DCS (respectively, aPR=1.15, 95% CI: 1.02-1.30; aPR=1.10, 95% CI: 1.00-1.22).
Conclusion: Although recent informal DCS use was infrequently reported in our study, willingness to use a formal DCS was high. Our findings indicate a potential role for laboratory-based DCS in mitigating overdose risk among individuals accessing the unregulated drug supply. However, barriers that impede service access or reduce interest should be addressed to ensure equitable use among those at heightened risk of overdose.
Highlights:
• Recent informal drug checking (e.g., fentanyl test strip) was infrequently reported.
• Willingness to use formal (i.e., laboratory-based) drug checking was high.
• Recent informal drug checking was associated with willingness to use formal drug checking.
• Barriers impeding service access must be addressed to ensure equitable use.
Affiliation :
Centre on Drug Policy Evaluation, St. Michael's Hospital, Toronto, ON, Canada
Cote :
Abonnement