Historique
Article de Périodique
Concentration of tetrahydrocannabinol in joints (2021)
Auteur(s) :
TEJEDOR TEJADA, E. ;
DE LA FUENTE MARCOS, D. ;
CUESTA LOZANO, M. J. ;
BENEDI GONZALEZ, J. ;
MORO AGUADO, J. ;
TEJEDOR MUNOZ, J. M.
Année
2021
Page(s) :
146-156
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus géographique
ESPAGNE
Thésaurus mots-clés
CANNABIDIOL
;
CANNABIS
;
TETRAHYDROCANNABINOL
;
MESURES QUANTITATIVES
;
CANNABINOIDES
;
ANALYSE CHIMIQUE
;
EVOLUTION
Résumé :
Purpose: This study aims to assess the potency and dose of Delta-9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD) in cannabis joints. This will enable better estimates of the degree of exposure in a user and contribute towards a better understanding of potential harmful effects.
Design/methodology/approach: Analysis of intact joints confiscated by law enforcement on the street in the autonomous region of Castilla y León (Spain) during the years 2017–2019.
Findings: This study analysed THC, CBN and CBD in marijuana joints (N = 744). Joints contain cannabis and tobacco (N = 729), had a median net weight 0.69?g (IQR = 0.28); concentration THC median was 6.30% (IQR = 4.51) and THC median dose 42?mg (IQR = 32.75). A total of 35.5% mixed joints contained CBN - median percentage 0.61% (IQR = 0.51). CBD was detected 10.3% of mixed joints - median percentage 0.13% (IQR = 0.12) and median dose 1?mg (IQR = 0.92). CBD/THC ratio presented median value of 0.02 (IQR = 0.02). The samples analysed comprised pure cannabis joints (N = 15), with THC median 11.86% (IWR = 6.30) or median dose of 118?mg.
Originality/value: The study found high values for concentration and dose of THC and CBD in cannabis joints, warning of high exposures for the user and associated potential consequences. The results obtained contribute new perspectives on the definition of a standard cannabis unit.
Design/methodology/approach: Analysis of intact joints confiscated by law enforcement on the street in the autonomous region of Castilla y León (Spain) during the years 2017–2019.
Findings: This study analysed THC, CBN and CBD in marijuana joints (N = 744). Joints contain cannabis and tobacco (N = 729), had a median net weight 0.69?g (IQR = 0.28); concentration THC median was 6.30% (IQR = 4.51) and THC median dose 42?mg (IQR = 32.75). A total of 35.5% mixed joints contained CBN - median percentage 0.61% (IQR = 0.51). CBD was detected 10.3% of mixed joints - median percentage 0.13% (IQR = 0.12) and median dose 1?mg (IQR = 0.92). CBD/THC ratio presented median value of 0.02 (IQR = 0.02). The samples analysed comprised pure cannabis joints (N = 15), with THC median 11.86% (IWR = 6.30) or median dose of 118?mg.
Originality/value: The study found high values for concentration and dose of THC and CBD in cannabis joints, warning of high exposures for the user and associated potential consequences. The results obtained contribute new perspectives on the definition of a standard cannabis unit.
Affiliation :
Health and Social Policy Area, Government Delegation in Castle and Lyon, Valladolid, Spain