Historique
Article de Périodique
Trajectories of cannabis use disorder: risk factors, clinical characteristics and outcomes (2017)
Auteur(s) :
KOSTY, D. B. ;
SEELEY, J. R. ;
FARMER, R. F. ;
STEVENS, J. J. ;
LEWINSOHN, P. M.
Année
2017
Page(s) :
279-287
Langue(s) :
Anglais
Refs biblio. :
50
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PSY (Psychopathologie / Psychopathology)
Thésaurus géographique
ETATS-UNIS
Thésaurus mots-clés
CANNABIS
;
ADOLESCENT
;
ADULTE
;
TRAJECTOIRE
;
FACTEUR DE RISQUE
;
AGE
;
ECHELLE D'EVALUATION
;
DIAGNOSTIC
;
PSYCHOPATHOLOGIE
Note générale :
Commentary: Understanding risk classes for cannabis use disorder requires knowledge of exposure, environment and genetic effects. Hines L.A., p. 288-289.
Résumé :
Aims: To estimate cannabis use disorder (CUD) trajectory classes from ages 14 to 30 years and compare classes on clinical characteristics, risk factors and psychosocial outcomes.
Design: Four waves (T1-T4) of data from an epidemiological study of psychopathology among a regionally representative sample. Trajectory classes described risk for CUD as a function of age. The number of classes was determined by model fit.
Setting: Participants were selected randomly from nine high schools in western Oregon, USA.
Participants: The sample included 816 participants [age at T1 mean = 16.6, standard deviation (SD) = 1.2; 44% male; 8% non-white].
Measurements: Participants completed diagnostic interviews, Child Trauma Questionnaire, Social Adjustment Scale and items adapted from the Wisconsin Manual for Assessing Psychotic-Like Experiences.
Findings: There were three CUD trajectory classes (Lo-Mendell-Rubin likelihood ratio test < 0.001): (1) persistent increasing risk; (2) maturing out, with increasing risk then decreasing risk; and (3) stable low risk. The persistent increasing class had later initial CUD onsets (n² = 0.16, P < 0.001) and greater cumulative CUD durations (n² = 0.26, P < 0.001). Male sex [odds ratio (OR) = 2.57, P = 0.018], externalizing disorders between ages 24 and 30 years (OR = 2.64, P < 0.001) and psychotic experiences during early adulthood (Cohen's d = 0.44, P = 0.016) discriminated between the persistent increasing and the maturing-out classes.
Conclusions: Evidence suggests three distinguishable types of trajectory for development of cannabis use disorder starting in early teens: (1) persistent increasing risk; (2) maturing out, with increasing risk then decreasing risk; and (3) stable low risk.
Design: Four waves (T1-T4) of data from an epidemiological study of psychopathology among a regionally representative sample. Trajectory classes described risk for CUD as a function of age. The number of classes was determined by model fit.
Setting: Participants were selected randomly from nine high schools in western Oregon, USA.
Participants: The sample included 816 participants [age at T1 mean = 16.6, standard deviation (SD) = 1.2; 44% male; 8% non-white].
Measurements: Participants completed diagnostic interviews, Child Trauma Questionnaire, Social Adjustment Scale and items adapted from the Wisconsin Manual for Assessing Psychotic-Like Experiences.
Findings: There were three CUD trajectory classes (Lo-Mendell-Rubin likelihood ratio test < 0.001): (1) persistent increasing risk; (2) maturing out, with increasing risk then decreasing risk; and (3) stable low risk. The persistent increasing class had later initial CUD onsets (n² = 0.16, P < 0.001) and greater cumulative CUD durations (n² = 0.26, P < 0.001). Male sex [odds ratio (OR) = 2.57, P = 0.018], externalizing disorders between ages 24 and 30 years (OR = 2.64, P < 0.001) and psychotic experiences during early adulthood (Cohen's d = 0.44, P = 0.016) discriminated between the persistent increasing and the maturing-out classes.
Conclusions: Evidence suggests three distinguishable types of trajectory for development of cannabis use disorder starting in early teens: (1) persistent increasing risk; (2) maturing out, with increasing risk then decreasing risk; and (3) stable low risk.
Affiliation :
Oregon Research Institute, Eugene, OR, USA
Cote :
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