Historique
Article de Périodique
Progress toward pharmacotherapies for cannabis-use disorder: an evidence-based review (2016)
Auteur(s) :
COPELAND, J. ;
POKORSKI, I.
Année
2016
Page(s) :
41-53
Sous-type de document :
Revue de la littérature / Literature review
Langue(s) :
Anglais
Refs biblio. :
111
Domaine :
Drogues illicites / Illicit drugs
Thésaurus mots-clés
CANNABIS
;
PHARMACOTHERAPIE
;
SEVRAGE
;
TRAITEMENT
;
INTERVENTION
;
CANNABINOIDES
;
AGONISTE
;
ANTAGONISTE
Résumé :
Cannabis is the most widely used and variably regulated drug in the world, with increasing trends of use being reported in the US, Australia, Asia, and Africa. Evidence has shown a decrease in the age of commencement of cannabis use in some developed countries and a prolongation of risk of initiation to cannabis use beyond adolescence among more recent users. Cannabis use is associated with numerous health risks and long-term morbidity, as well as risk of developing cannabis-use disorders. Cannabis users infrequently seek professional treatment, and normally do so after a decade of use. Cannabis-use disorders are currently treated using a selection of psychosocial interventions. Severity of withdrawal is a factor that increases the risk of relapse, and is the target of pharmacotherapy studies. Currently, there is no approved pharmacotherapy for cannabis-use disorders. A number of approaches have been examined, and trials are continuing to find a safe and effective medication with little abuse liability.
Affiliation :
UNSW Medicine, University of New South Wales, Sydney, NSW, Australia