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![The never-ending public health issue of adulterants in abused drugs [Letter]](https://bdoc.ofdt.fr/img_cache/pmb_ofdt_record_77572.webp?v=1771252475)
Article de Périodique
The never-ending public health issue of adulterants in abused drugs [Letter] (2016)
Auteur(s) :
BUSARDO, F. P. ;
PICHINI, S. ;
PACIFICI, R. ;
KARCH, S. B.
Année
2016
Page(s) :
561-562
Langue(s) :
Anglais
Refs biblio. :
12
Domaine :
Drogues illicites / Illicit drugs
Discipline :
SAN (Santé publique / Public health)
Thésaurus mots-clés
PRODUIT ILLICITE
;
ADULTERANT
;
COCAINE
;
MDMA-ECSTASY
;
EFFET SECONDAIRE
;
DROGUES DE SYNTHESE
Résumé :
Illicit drugs have always contained other substances in addition to the claimed active ingredient, leading to potential health threats or even to premature death. Adulterants are often intentionally added to bulk, dilute, complement or enhance the effects of drugs, but sometimes the explanation for their presence is simply poor manufacturing practice.
The presence of adulterants has evolved over the years, mostly because new compounds have become available or consumer preference has changed. Most adulterants, normally found in cocaine and heroin and to some degree in all other abused drugs with potential adverse health effects, have been well characterized over time. Inactive bulking agents, such as sugars and talc, readily available compounds, like paracetamol, aspirin and caffeine, or pharmacologically active adulterants, which in large doses may have lifethreatening side effects (e.g., phenobarbital, quinine, clenbuterol, phenacetin, lidocaine, levamisole, etc.). [Extract]
The presence of adulterants has evolved over the years, mostly because new compounds have become available or consumer preference has changed. Most adulterants, normally found in cocaine and heroin and to some degree in all other abused drugs with potential adverse health effects, have been well characterized over time. Inactive bulking agents, such as sugars and talc, readily available compounds, like paracetamol, aspirin and caffeine, or pharmacologically active adulterants, which in large doses may have lifethreatening side effects (e.g., phenobarbital, quinine, clenbuterol, phenacetin, lidocaine, levamisole, etc.). [Extract]
Affiliation :
Unit of Forensic Toxicology (UoFT), Sapienza University of Rome, Rome, Italy