Auteur R. PACIFICI

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Adulteration practices of psychoactive illicit drugs: An updated review

R. SOLIMINI ; M. C. ROTOLO ; M. PELLEGRINI ; A. MINUTILLO ; R. PACIFICI ; F. P. BUSARDO ; S. ZAAMI | 2017
Dans Current Pharmaceutical Biotechnology (Vol.18, n°7, 2017) Article : Périodique

BACKGROUND: Powdery drugs such as cocaine and heroin are frequently adulterated or diluted predominantly to obtain more doses and to increase the drug dealer's profits, but also to enhance, to modify or to oppose drug effects. The aim of this re[...]

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Drugs of abuse in maternal hair and paired neonatal meconium: an objective assessment of foetal exposure to gestational consumption

X. JOYA ; E. MARCHEI ; J. SALAT-BATLLE ; O. GARCIA-ALGAR ; V. CALVARESI ; R. PACIFICI ; S. PICHINI | 2016
Dans Drug Testing and Analysis (Vol.8, n°7-8, July-August 2016) Article : Périodique

In a prospective sample of 80 mother-infant dyads, we investigated whether drugs of abuse in maternal hair measured during the pregnancy trimesters were also present in neonatal meconium. Principal drugs of abuse were analyzed in the three conse[...]

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Electronic cigarettes in Italy: a tool for harm reduction or a gateway to smoking tobacco?

X. LIU ; A. LUGO ; E. DAVOLI ; G. GORINI ; R. PACIFICI ; E. FERNANDEZ ; S. GALLUS | 2020
Dans Tobacco Control (Vol.29, n°2, March 2020) Article : Périodique

Introduction: More than a decade after electronic cigarettes (e-cigarette) hit the European market, we are still debating whether they may help or hinder tobacco control. It is therefore useful to explore the potential net effect of e-cigarette [...]

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A follow-up study of heroin addicts (VEdeTTE2): study design and protocol

VIGNA-TAGLIANTI F. D. ; F. MATHIS ; DIECIDUE R. ; BURRONI P. ; IANNACCONE A. ; LAMPIS F. ; P. ZUCCARO ; R. PACIFICI ; E. VERSINO ; M. DAVOLI ; F. FAGGIANO | 2007
Dans Substance Abuse Treatment, Prevention, and Policy (Vol.2, n°9, 2007) Article : Périodique

ENGLISH : BACKGROUND: In Italy, a large cohort study (VEdeTTE1) was conducted between 1998-2001 to evaluate the effectiveness of treatments in reducing mortality and increasing treatment retention among heroin addicts. The follow-up of this co[...]

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Letter to the editor: HAIRVEQ 2005: An external quality control exercise for drugs of abuse analysis in hair in cooperation with Society of Hair Testing

S. PICHINI ; M. VENTURA ; M. PUJADAS ; R. VENTURA ; R. DI GIOVANNANDREA ; P. ZUCCARO ; R. PACIFICI ; R. DE LA TORRE ; C. JURADO | 2005
Dans Annales de Toxicologie Analytique (Vol.17, n°4, 2005) Article : Périodique

Comparaison des méthodes de dépistage de stupéfiants dans les cheveux, d'un point de vue qualitatif et quantitatif, de deux groupes de laboratoires (Italian National Health Service et Sociey of Hair Testing).

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Modulation ot the immune system in cannabis users

R. PACIFICI ; P. ZUCCARO ; S. PICHINI ; P. N. ROSET ; POUDEVIDA S. ; M. FARRE ; J. SEGURA ; R. DE LA TORRE | 2003
Périodique

ENGLISH : Cannabis use was associated with a decrease in levels of IL-2, a TH1-type cytokine related to cell-mediated immunity, and an increase in levels of IL-10, a TH2-type cytokine related to humoral immunity. The decrease of proinflammator[...]

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New synthetic opioids use among patients in treatment for an opioid use disorder in Barcelona

M. ALIAS-FERRI ; E. MARCHEI ; R. PACIFICI ; S. PICHINI ; M. PELLEGRINI ; C. PEREZ-MANA ; E. PAPASEIT ; R. MUGA ; F. FONSECA ; M. FARRE ; M. TORRENS | 2022
Dans European Addiction Research (Vol.28, n°5, September 2022) Article : Périodique

INTRODUCTION: New synthetic opioids (NSO), a class of new psychoactive substances (NPS), have recently emerged and pose an upcoming global public health challenge. The effects produced by NSO are similar to those from morphine, but they present [...]

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Purity and adulterant analysis of some recent drug seizures in Italy

S. PICHINI ; F. P. BUSARDO ; A. GREGORI ; P. BERRETTA ; S. GENTILI ; R. PACIFICI | 2017
Dans Drug Testing and Analysis (Vol.9, n°3-4, March-April 2017) Article : Périodique

The data collected in this study describe an initial attempt to systematically introduce the qualitative and quantitative analysis of adulterants present in seized street drugs in Italy with the aim of improving surveillance and data sharing and[...]

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Rapid screening method for determination of ecstasy and amphetamines in urine samples using gas chromatography-chemical ionisation mass spectrometry

M. PELLEGRINI ; ROSATI F. ; R. PACIFICI ; P. ZUCCARO ; ROMOLO F. S. ; A. LOPEZ | 2002
Périodique

ENGLISH : The need for analytical screening tests more reliable and valid to detect amphetamine and related "designer drugs" in biological samples is becoming critical, due to the increasing diffusion of these drugs on the European illegal mar[...]

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Serum cotinine as a marker of environmental tobacco smoke exposure in epidemiological studies: the experience of the MATISS project

SECCARECCIA F. ; P. ZUCCARO ; R. PACIFICI | 2003
Dans European Journal of Epidemiology (Vol.18, n°6, June 2003) Article : Périodique

To describe serum cotinine levels in a rural Italian population and to examine its usefulness as an epidemiologic biomarker of nicotine exposure, cross-sectional data collected in 1993 for the MATISS Project (2098 men and 1352 women, aged 20–79 [...]

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The never-ending public health issue of adulterants in abused drugs [Letter]

F. P. BUSARDO ; S. PICHINI ; R. PACIFICI ; S. B. KARCH | 2016
Dans Journal of Analytical Toxicology (Vol.40, n°7, September 2016) Article : Périodique

Illicit drugs have always contained other substances in addition to the claimed active ingredient, leading to potential health threats or even to premature death. Adulterants are often intentionally added to bulk, dilute, complement or enhance t[...]

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Variations de la teneur en tétrahydrocannabinol des plants de Cannabis permettant de distinguer les plantes de type à fibre des plantes de type à drogue

U. AVICO ; R. PACIFICI ; P. ZUCCARO | 1985
Dans Bulletin des Stupéfiants (Vol.37, n°4, 1985) Article : Périodique

FRANÇAIS : Les auteurs rappellent que les effets psychoactifs du cannabis dépendent de sa teneur en tetrahydrocannabinol. Ils distinguent deux grands types de plantes, celles dites à drogue dont la teneur en THC est comprise entre 0,058 et 0,2[...]

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