Historique
Article de Périodique
Relationship between cannabis and psychosis: Reasons for use and associated clinical variables (2015)
Auteur(s) :
MANÉ, A. ;
FERNANDEZ-EXPOSITO, M. ;
BERGÉ, D. ;
GOMEZ-PEREZ, L. ;
SABATÉ, A. ;
TOLL, A. ;
DIAZ, L. ;
DIEZ-AJA, C. ;
PEREZ, V.
Année
2015
Page(s) :
70-74
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PSY (Psychopathologie / Psychopathology)
Thésaurus mots-clés
TROUBLE BIPOLAIRE
;
ETUDE CLINIQUE
;
CANNABIS
;
PSYCHOSE
;
SCHIZOPHRENIE
;
AUTOMEDICATION
;
PSYCHOPATHOLOGIE
;
AGE
;
MOTIVATION
Thésaurus géographique
ESPAGNE
Résumé :
The mechanism underneath the relationship between cannabis and psychosis remains controversial, for which several hypotheses have been proposed, including cannabis as self-medication and cannabis as a risk for the development of psychosis. The aim of this work was to study the relationship between cannabis and psychosis in first-episode psychosis cannabis users and non-users, and non-psychotic cannabis users. The age at the first psychotic episode, duration of untreated psychosis, psychopathology and reasons for cannabis use were assessed. First-episode psychosis cannabis users showed an earlier age at psychosis onset than non-user patients. No significant differences in symptomatology were found. The distinguishing reasons to use cannabis for patients with first-episode psychosis with respect to non-psychotic users were to arrange their thoughts and deal with hallucinations and suspiciousness. These findings are in agreement with both hypotheses: self-medication and secondary psychosis hypothesis. However, longitudinal prospective cohort studies assessing reasons for cannabis use are needed to investigate both hypotheses and their complementarity.
Highlights:
First-episode psychosis cannabis users showed an earlier age at psychosis onset than non-users.
First-episode psychosis patients had distinguishing reasons to use cannabis.
Highlights:
First-episode psychosis cannabis users showed an earlier age at psychosis onset than non-users.
First-episode psychosis patients had distinguishing reasons to use cannabis.
Affiliation :
IMIM (Hospital del Mar Medical Research Institute) - Neurosciences, Psychiatry, Barcelona, Spain