Historique
Article de Périodique
Cannabis withdrawal symptoms in non-treatment-seeking adult cannabis smokers (2010)
Auteur(s) :
LEVIN, K. H. ;
COPERSINO, M. L. ;
HEISHMAN, S. J. ;
LIU, F. ;
KELLY, D. L. ;
BOGGS, D. L. ;
GORELICK, D. A.
Année
2010
Page(s) :
120-127
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Thésaurus géographique
ETATS-UNIS
Thésaurus mots-clés
CANNABIS
;
SYNDROME DE SEVRAGE
;
ADULTE
;
RECHUTE
;
TOLERANCE
;
SEVRAGE
Résumé :
Background: Cannabis withdrawal is not recognized in DSM-IV because of doubts about its clinical significance.
Objectives: Assess the phenomenon of cannabis withdrawal and its relationship to relapse in non-treatment-seeking adults.
Subjects: Convenience sample of 469 adult cannabis smokers who had made a quit attempt while not in a controlled environment.
Methods: Subjects completed a 176-item Marijuana Quit Questionnaire collecting information on sociodemographic characteristics, cannabis use history, and their "most difficult" cannabis quit attempt.
Results: 42.4% of subjects had experienced a lifetime withdrawal syndrome, of whom 70.4% reported using cannabis in response to withdrawal. During the index quit attempt, 95.5% of subjects reported >=1 individual withdrawal symptom (mean [SD] 9.5 [6.1], median 9.0); 43.1% reported >=10. Number of withdrawal symptoms was significantly associated with greater frequency and amount of cannabis use, but symptoms occurred even in those using less than weekly. Symptoms were usually of >= moderate intensity and often prompted actions to relieve them. Alcohol (41.5%) and tobacco (48.2%) were used more often than cannabis (33.3%) for this purpose. There was little change during withdrawal in use of other legal or illegal substances.
Conclusions: Cannabis withdrawal is a common syndrome among adults not seeking treatment. The intention to relieve withdrawal symptoms can drive relapse during quit attempts, giving cannabis withdrawal clinical significance as a target of treatment.
Objectives: Assess the phenomenon of cannabis withdrawal and its relationship to relapse in non-treatment-seeking adults.
Subjects: Convenience sample of 469 adult cannabis smokers who had made a quit attempt while not in a controlled environment.
Methods: Subjects completed a 176-item Marijuana Quit Questionnaire collecting information on sociodemographic characteristics, cannabis use history, and their "most difficult" cannabis quit attempt.
Results: 42.4% of subjects had experienced a lifetime withdrawal syndrome, of whom 70.4% reported using cannabis in response to withdrawal. During the index quit attempt, 95.5% of subjects reported >=1 individual withdrawal symptom (mean [SD] 9.5 [6.1], median 9.0); 43.1% reported >=10. Number of withdrawal symptoms was significantly associated with greater frequency and amount of cannabis use, but symptoms occurred even in those using less than weekly. Symptoms were usually of >= moderate intensity and often prompted actions to relieve them. Alcohol (41.5%) and tobacco (48.2%) were used more often than cannabis (33.3%) for this purpose. There was little change during withdrawal in use of other legal or illegal substances.
Conclusions: Cannabis withdrawal is a common syndrome among adults not seeking treatment. The intention to relieve withdrawal symptoms can drive relapse during quit attempts, giving cannabis withdrawal clinical significance as a target of treatment.
Affiliation :
Intramural Research Program, National Institute on Drug Abuse, 251 Bayview Blvd., Baltimore, MD 21224, USA
Cote :
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