Historique
Article de Périodique
Methylenedioxypyrovalerone ("Bath salts") related death: case report and review of the literature (2013)
Auteur(s) :
KESHA, K. ;
BOGGS, C. L. ;
RIPPLE, M. G. ;
ALLAN, C. H. ;
LEVINE, B. ;
JUFER-PHIPPS, R. ;
DOYON, S. ;
CHI, P. ;
FOWLER, D. R.
Année
2013
Page(s) :
1654-1659
Sous-type de document :
Etude de cas / Case report ; Revue de la littérature / Literature review
Langue(s) :
Anglais
Refs biblio. :
45
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus géographique
ETATS-UNIS
Thésaurus mots-clés
ETUDE DE CAS
;
CATHINONES
;
DROGUES DE SYNTHESE
;
MORTALITE
;
TOXICOLOGIE
;
INTOXICATION
;
HYPERTHERMIE
;
ANALYSE CHIMIQUE
Résumé :
Cathinone derivatives (bath salts) have emerged as the latest drugs of abuse. 3,4-methylenedioxypyrovalerone (MDPV) is the primary active ingredient in bath salts used in this country. This article presents the second reported cause of death by MDPV intoxication alone. In April 2011, a delusional man was emergently brought to a hospital, where he self-reported bath salt usage. He became agitated, developed ventricular tachycardia, hyperthermia, and died. Comprehensive alcohol and drug testing was performed. Using the alkaline drug screen, heart blood contained 0.7 mg/L MDPV and peripheral blood contained 1.0 mg/L MDPV. His bizarre behavior with life-threatening hyperthermia was consistent with an MDPV-induced excited delirium state. MDPV is not yet found by routine immunoassay toxicology screens. Testing for MDPV should be considered in cases with a history of polysubstance abuse with stimulant type drugs, report of acute onset of psychogenic symptoms, excited delirium syndrome, or presentation in a hyperthermic state.
Affiliation :
Maryland Office of the Chief Medical Examiner, Baltimore, MD, USA