Historique
Article de Périodique
Peer-education intervention to reduce injection risk behaviors benefits high-risk young injection drug users: a latent transition analysis of the CIDUS 3/DUIT study (2013)
Auteur(s) :
MACKESY-AMITI, M. E. ;
FINNEGAN, L. ;
OUELLET, L. J. ;
GOLUB, E. T. ;
HAGAN, H. ;
HUDSON, S. M. ;
LATKA, M. H. ;
GARFEIN, R. S.
Année
2013
Page(s) :
2075-2083
Langue(s) :
Anglais
Refs biblio. :
50
Domaine :
Drogues illicites / Illicit drugs
Thésaurus géographique
ETATS-UNIS
Thésaurus mots-clés
REDUCTION DES RISQUES ET DES DOMMAGES
;
INTERVENTION
;
PAIR
;
INJECTION
;
VIH
;
HEPATITE
;
CONDUITE A RISQUE
;
MODELE
Résumé :
We analyzed data from a large randomized HIV/HCV prevention intervention trial with young injection drug users (IDUs) conducted in five U.S. cities. The trial compared a peer education intervention (PEI) with a time-matched, attention control group. Applying categorical latent variable analysis (mixture modeling) to baseline injection risk behavior data, we identified four distinct classes of injection-related HIV/HCV risk: low risk, non-syringe equipment-sharing, moderate-risk syringe-sharing, and high-risk syringe-sharing. The trial participation rate did not vary across classes. We conducted a latent transition analysis using trial baseline and 6-month follow-up data, to test the effect of the intervention on transitions to the low-risk class at follow-up. Adjusting for gender, age, and race/ethnicity, a significant intervention effect was found only for the high-risk class. Young IDU who exhibited high-risk behavior at baseline were 90% more likely to be in the low-risk class at follow-up after the PEI intervention, compared to the control group.
Affiliation :
Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL, USA