Historique
Article de Périodique
Mental health differences between frequent cannabis users with and without dependence and the general population (2013)
Auteur(s) :
VAN DER POL, P. ;
LIEBREGTS, N. ;
DE GRAAF, R. ;
TEN HAVE, M. ;
KORF, D. J. ;
VAN DEN BRINK, W. ;
VAN LAAR, M.
Année
2013
Page(s) :
1459-1469
Langue(s) :
Anglais
Refs biblio. :
58
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PSY (Psychopathologie / Psychopathology)
Thésaurus géographique
PAYS-BAS
Thésaurus mots-clés
CANNABIS
;
ETUDE TRANSVERSALE
;
SANTE MENTALE
;
PSYCHOPATHOLOGIE
;
COMPARAISON
;
DEPENDANCE
;
POPULATION GENERALE
;
USAGE REGULIER
;
TYPE D'USAGE
Résumé :
Aims: To compare the prevalence of mental disorders between frequent cannabis users with and without dependence and the general population.
Design: Cross-sectional comparison of interview data.
Setting: Enriched community sample of frequent cannabis users and a representative sample of non-users and non-frequent users from the general population.
Participants: A total of 521 young adult (aged 18-30 years) frequent cannabis users, 252 of whom were with DSM-IV cannabis dependence (D+) and 269 without DSM-IV cannabis dependence (D-), and 1072 young adults from the general population.
Measurements: Multinomial logistic regression was used to compare groups regarding the presence of DSM-IV mental disorders. Detailed measures of cannabis use, childhood adversity and other substance use were considered confounders.
Findings: Compared with the general population, externalizing disorders were more prevalent in D- [odds ratio (OR) = 8.91, P < 0.001] and most prevalent in D+ (OR = 17.75, P < 0.001), but internalizing disorders were associated only with D+ (mood OR = 4.15, P < 0.001; anxiety OR = 2.20, P = 0.002). Associations were attenuated (and often became non-significant) after correction for childhood adversity and substance use other than cannabis. However, the prevalence of mental disorders remained higher in D+ compared with D- (OR = 2.40, P < 0.001), although cannabis use patterns were remarkably similar.
Conclusions: Cannabis use patterns, childhood adversity and the use of other substances are similar in dependent and non-dependent frequent cannabis users. With the exception of more externalizing disorders, the mental health condition of non-dependent frequent cannabis users is similar to that of the general population, whereas it is worse in dependent frequent cannabis users.
KEY FINDINGS:
Dependent frequent cannabis users have worse mental health than both non-dependent frequent cannabis users and the general population.
Design: Cross-sectional comparison of interview data.
Setting: Enriched community sample of frequent cannabis users and a representative sample of non-users and non-frequent users from the general population.
Participants: A total of 521 young adult (aged 18-30 years) frequent cannabis users, 252 of whom were with DSM-IV cannabis dependence (D+) and 269 without DSM-IV cannabis dependence (D-), and 1072 young adults from the general population.
Measurements: Multinomial logistic regression was used to compare groups regarding the presence of DSM-IV mental disorders. Detailed measures of cannabis use, childhood adversity and other substance use were considered confounders.
Findings: Compared with the general population, externalizing disorders were more prevalent in D- [odds ratio (OR) = 8.91, P < 0.001] and most prevalent in D+ (OR = 17.75, P < 0.001), but internalizing disorders were associated only with D+ (mood OR = 4.15, P < 0.001; anxiety OR = 2.20, P = 0.002). Associations were attenuated (and often became non-significant) after correction for childhood adversity and substance use other than cannabis. However, the prevalence of mental disorders remained higher in D+ compared with D- (OR = 2.40, P < 0.001), although cannabis use patterns were remarkably similar.
Conclusions: Cannabis use patterns, childhood adversity and the use of other substances are similar in dependent and non-dependent frequent cannabis users. With the exception of more externalizing disorders, the mental health condition of non-dependent frequent cannabis users is similar to that of the general population, whereas it is worse in dependent frequent cannabis users.
KEY FINDINGS:
Dependent frequent cannabis users have worse mental health than both non-dependent frequent cannabis users and the general population.
Affiliation :
Netherlands Institute of Mental Health and Addiction, Utrecht, the Netherlands
Cote :
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