Historique
Article de Périodique
Effectiveness of drug tests in outpatients starting opioid substitution therapy (2013)
Auteur(s) :
DUPOUY, J. ;
DASSIEU, L. ;
BOURREL, R. ;
POUTRAIN, J. C. ;
BISMUTH, S. ;
OUSTRIC, S. ;
LAPEYRE-MESTRE, M.
Année
2013
Page(s) :
515-521
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
EPI (Epidémiologie / Epidemiology)
Thésaurus géographique
FRANCE
;
MIDI-PYRENEES
Thésaurus mots-clés
OPIOIDES
;
DEPISTAGE
;
TRAITEMENT DE MAINTENANCE
;
BASE DE DONNEES
;
ASSURANCE MALADIE
;
TEST
;
EFFICACITE
;
TRAITEMENT AMBULATOIRE
;
COHORTE
;
PSYCHOTROPES
Résumé :
We aimed to assess the effectiveness of drug tests for treatment retention in outpatients starting opioid substitution therapy. A retrospective cohort was created from the data of the French health insurance system database for the Midi-Pyrenees region. Patients starting opioid substitution treatment (OST) were included and followed for 18 to 30 months. Two groups of patients were defined: the drug test group (at least one drug test reimbursement) and a control group (no drug test reimbursement). The cohort included 1507 patients. During follow-up, 39 subjects (2.6%) had at least one drug test reimbursement. Mean treatment retention was 207 days in the control group and 411 days in the drug test group (p < 0.001). With a multivariate Cox model, drug tests were associated with treatment retention: hazard ratio 0.55 (95% CI: 0.38-0.80). Use of a drug test in follow-up of opioid substitution treatment, although rarely prescribed, significantly improved treatment retention.
Affiliation :
Département Universitaire de Médecine Générale, Université de Toulouse, Faculté de Médecine, Toulouse, France