Historique
Article de Périodique
Agranulocytosis after cocaine use: a case of suspected levamisole contamination in Belgium (2012)
Auteur(s) :
BRABANT, W. ;
MAZURE, D. ;
VANTILBORGH, A. ;
VAN HEERINGEN, C. ;
LEMMENS, G. M.
Année
2012
Page(s) :
1159-1160
Sous-type de document :
Etude de cas / Case report
Langue(s) :
Anglais
Refs biblio. :
5
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PAT (Pathologie organique / Organic pathology)
Thésaurus géographique
BELGIQUE
Thésaurus mots-clés
COCAINE
;
LEVAMISOLE
;
ADULTERANT
;
ETUDE DE CAS
;
SYMPTOME
;
EFFET SECONDAIRE
;
SYSTEME IMMUNITAIRE
Résumé :
Since 2005 cocaine use has significantly increased in Western Europe, especially in recreational settings and among young people (aged 15-34). With an average yearly prevalence of 1.3%, it is now the second most-used illicit drug after cannabis. Cocaine has been reported to cause a wide variety of psychiatric problems (e.g. suicidal ideation, addiction, depression, psychosis), cardiovascular (e.g. arrhythmias, myocardial infarction, myocarditis) and cerebrovascular complications (e.g. cerebral infarction, subarachnoid haemorrhage) and rheumatologic syndromes (e.g. Raynaud's phenomenon, vasculitis). Moreover, several unexplained cases of agranulocytosis have emerged in cocaine abusers in New Mexico, Canada and the United States. Epidemiologic investigation indicated that cocaine contaminated with levamisole was the likely cause of the agranulocytosis. We report the first case of agranulocytosis in a patient after cocaine use in Belgium. [Introduction]
Affiliation :
Department of Psychiatry, Ghent University Hospital, Ghent, Belgium