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Article de Périodique
Pathways to heroin dependence: time to re-appraise self-medication [For debate] (2013)
Auteur(s) :
DARKE, S. (Auteur) ;
KHANTZIAN, E. J. (Auteur du commentaire) ;
BRESLAU, N. (Auteur du commentaire) ;
LEMBKE, A. (Auteur du commentaire) ;
AGRAWAL, A. (Auteur du commentaire) ;
LYNSKEY, M. T. (Auteur du commentaire) ;
NELSON, E. C. (Auteur du commentaire) ;
BERGMARK, A. (Auteur du commentaire)
Année
2013
Page(s) :
659-667
Sous-type de document :
Revue de la littérature / Literature review
Langue(s) :
Anglais
Refs biblio. :
103
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PSY (Psychopathologie / Psychopathology)
Thésaurus mots-clés
HEROINE
;
PSYCHOPATHOLOGIE
;
AUTOMEDICATION
;
THEORIE
;
DEPENDANCE
;
TRAJECTOIRE
;
MODELE
;
TRAUMATISME
Note générale :
COMMENTARIES:
• Addiction as a self-regulation disorder and the role of self-medication. Khantzian E.J., p. 668-669.
• The role of trauma in drug use disorders. Breslau N., p. 669-670.
• From self-medication to intoxication: time for a paradigm shift. Lembke A., p. 670-671.
• Shattered childhoods and the genetics of heroin dependence. Agrawal A., Lynskey M.T., Nelson E.C., p. 671-673.
• The role of psychopathology as motivator for drug dependency - Some moderating remarks. Bergmark A., p. 673-674.
• Addiction as a self-regulation disorder and the role of self-medication. Khantzian E.J., p. 668-669.
• The role of trauma in drug use disorders. Breslau N., p. 669-670.
• From self-medication to intoxication: time for a paradigm shift. Lembke A., p. 670-671.
• Shattered childhoods and the genetics of heroin dependence. Agrawal A., Lynskey M.T., Nelson E.C., p. 671-673.
• The role of psychopathology as motivator for drug dependency - Some moderating remarks. Bergmark A., p. 673-674.
Résumé :
The self-medication hypothesis emphasizes the role of distressing affect as the primary motivator for the compulsive use that leads to substance dependence. The model also postulates that there will be psychopharmacological specificity between symptom presentation and the primary drug of dependence. In this review, the self-medication hypothesis is examined in relation to the development and chronicity of heroin dependence. It is argued that if self-medication has a role in engendering and extending substance dependence, it should be apparent in the use of a drug that carries such overwhelming personal risk. The psychopathology seen among adult users is certainly consistent with the model. More importantly, however, are the extraordinarily high levels of childhood trauma and psychopathology that occur typically well before the initiation of heroin use. In contrast, the postulate of drug specificity appears less supported by the polydrug use patterns typical of heroin users, and does not appear to be a necessary corollary of the model.
Affiliation :
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia
Cote :
Abonnement