Historique
Article de Périodique
Ketamine-like effects after recreational use of methoxetamine (2012)
Auteur(s) :
HOFER, K. E. ;
GRAGER, B. ;
MULLER, D. M. ;
RAUBER-LUTHY, C. ;
KUPFERSCHMIDT, H. ;
RENTSCH, K. M. ;
CESCHI, A.
Année
2012
Page(s) :
97-99
Sous-type de document :
Etude de cas / Case report
Langue(s) :
Anglais
Refs biblio. :
15
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus géographique
SUISSE
Thésaurus mots-clés
METHOXETAMINE
;
ETUDE DE CAS
;
DROGUES DE SYNTHESE
;
USAGE RECREATIF
;
SYMPTOME
;
EFFET SECONDAIRE
;
PHARMACOLOGIE
;
TOXICOLOGIE
;
ANALYSE CHIMIQUE
Résumé :
Methoxetamine, the N-ethyl derivative of ketamine, is a novel recreational drug that is not at present subject to restrictive regulations in most countries. To our knowledge, no case of methoxetamine abuse has been published to date in the scientific literature, and the only sources of information are illegal drug users' Web discussion forums. We report the first case of analytically confirmed intravenous methoxetamine abuse in a 19-year-old man. Observed signs and symptoms such as tachycardia, hypertension, confusion, agitation, stupor, ataxia, mydriasis, and nystagmus were consistent with ketamine-induced adverse effects and resolved with symptomatic treatment. According to this case report, user Web reports, and the chemical structure, methoxetamine produces ketamine-like effects. Complete recovery can be expected with supportive care.
Affiliation :
Swiss Toxicological Information Centre, Associated Institute of the University of Zurich, Zurich, Switzerland