Historique
Article de Périodique
Quality of life among alcohol-dependent patients: How satisfactory are the available instruments? A systematic review (2012)
Auteur(s) :
LUQUIENS, A. ;
REYNAUD, M. ;
FALISSARD, B. ;
AUBIN, H. J.
Année
2012
Page(s) :
192-202
Sous-type de document :
Revue de la littérature / Literature review
Langue(s) :
Anglais
Domaine :
Alcool / Alcohol
Résumé :
Aim: The purpose of this systematic review was to compare quality-of-life instruments used as outcome measures in randomized clinical trials for alcohol-dependence treatment.
Methods: Randomized controlled clinical trials, indexed in the EMBASE, PubMed and PsycINFO databases since 1981, which aimed at improving the quality of life in alcohol-dependent patients and used as instrument to measure the quality of life, as specifically designated by the authors, were included.
Results: Of the 331 articles screened, 18 studies were included in the review. Eight different quality-of-life instruments were used as outcome measures. Twenty-seven life domains were explored. Between-scale heterogeneity was high. The scale most frequently used was the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Only 1 clinical trial demonstrated a significant difference between intervention groups at all endpoints, using the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q).
Conclusion: Because many different instruments were used, it is difficult to compare quality-of-life improvement between trials. The most frequently used instrument was a generic health status measure that may not be well suited as a quality-of-life measure for subjects with alcohol dependence. The construction and validation of a specific patient-reported outcome based on alcohol-dependent patients' concerns would effectively contribute to the assessment of treatment efficacy.
Methods: Randomized controlled clinical trials, indexed in the EMBASE, PubMed and PsycINFO databases since 1981, which aimed at improving the quality of life in alcohol-dependent patients and used as instrument to measure the quality of life, as specifically designated by the authors, were included.
Results: Of the 331 articles screened, 18 studies were included in the review. Eight different quality-of-life instruments were used as outcome measures. Twenty-seven life domains were explored. Between-scale heterogeneity was high. The scale most frequently used was the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Only 1 clinical trial demonstrated a significant difference between intervention groups at all endpoints, using the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q).
Conclusion: Because many different instruments were used, it is difficult to compare quality-of-life improvement between trials. The most frequently used instrument was a generic health status measure that may not be well suited as a quality-of-life measure for subjects with alcohol dependence. The construction and validation of a specific patient-reported outcome based on alcohol-dependent patients' concerns would effectively contribute to the assessment of treatment efficacy.
Affiliation :
Hôpital Paul Brousse, Univ. Paris-Sud, INSERM U669, Villejuif, France
Cote :
Abonnement