Article de Périodique
Are pharmacokinetic approaches feasible for treatment of cocaine addiction and overdose? [Editorial] (2012)
Auteur(s) :
ZHENG, F. ;
ZHAN, C. G.
Année
2012
Page(s) :
125-128
Sous-type de document :
Editorial
Langue(s) :
Anglais
Refs biblio. :
16
Domaine :
Drogues illicites / Illicit drugs
Thésaurus mots-clés
COCAINE
;
PHARMACOCINETIQUE
;
METABOLISME
;
SURDOSE
;
PHARMACOTHERAPIE
;
DEPENDANCE
;
NEUROBIOLOGIE
;
ENZYMES
;
TRAITEMENT
;
RECHERCHE
Résumé :
We discuss the main challenges for developing therapeutic treatment of cocaine addiction and explain why pharmacokinetic approaches, particularly those based on our recently developed efficient cocaine-metabolizing enzymes, are feasible for treatment of cocaine addiction and overdose.
Affiliation :
Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY, USA
Historique