Historique
Article de Périodique
Prenatal exposure to methadone and buprenorphine: A review of the potential effects on cognitive development (2011)
Auteur(s) :
KONIJNENBERG, C. ;
MELINDER, A.
Année
2011
Page(s) :
495-519
Sous-type de document :
Revue de la littérature / Literature review
Langue(s) :
Anglais
Domaine :
Autres substances / Other substances ; Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
METHADONE
;
BUPRENORPHINE
;
PRODUIT DE SUBSTITUTION
;
GROSSESSE
;
DEVELOPPEMENT
;
COGNITION
;
CROISSANCE
;
NOUVEAU-NE
;
ENFANT
;
PREMATURITE
;
NEUROTRANSMETTEURS
Résumé :
The amount of opioid users receiving opioid maintenance therapy has increased significantly over the last few years. As a result, an increasing number of children are prenatally exposed to long-lasting opioids such as methadone and buprenorphine. This article reviews the literature on the cognitive development of children born to mothers in opioid maintenance therapy. Topics discussed are the effects of prenatal exposure on prematurity, somatic growth, brain volume, myelination, and the endocrine and neurotransmitter system. Social-environmental factors, including parental functioning, as well as genetic factors are also described. Areas requiring further research are identified.
Affiliation :
Norwegian Centre for Addiction Research, Institute of Psychiatry, University of Oslo, Oslo, Norway