Historique
Article de Périodique
Mephedrone: use, subjective effects and health risks (2011)
(Méphédrone : usage, effets subjectifs et risques pour la santé)
Auteur(s) :
WINSTOCK, A. ;
MITCHESON, L. ;
RAMSEY, J. ;
DAVIES, S. ;
PUCHNAREWICZ, M. ;
MARSDEN, J.
Année
2011
Page(s) :
1991-1996
Langue(s) :
Anglais
Refs biblio. :
13
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus géographique
ROYAUME-UNI
Thésaurus mots-clés
MEPHEDRONE
;
ETUDE TRANSVERSALE
;
TELEPHONE
;
ENQUETE
;
TOXICOLOGIE
;
EFFET SECONDAIRE
;
CONSOMMATION
;
PREVALENCE
;
DEPENDANCE
Résumé :
AIMS To assess the patterns of use, subjective effect profile and dependence liability of mephedrone, supported by corroborative urine toxicology.
DESIGN Cross-sectional structured telephone interview. Setting UK-based drug users associated with the dance music scene.
PARTICIPANTS A total of 100 mephedrone users, recruited through their involvement with the dance music scene.
MEASUREMENTS Assessment of pattern of use, acute and after effects, DSM dependence criteria and gas chromatography-mass spectrometry urinalysis.
FINDINGS Mephedrone consumption results in typical stimulant-related subjective effects: euphoria, increased concentration, talkativeness, urge to move, empathy, jaw clenching, reduced appetite and insomnia. Thirty per cent of the sample potentially met criteria for DSM-IV dependence and there was evidence of a strong compulsion to use the drug (47% had used the drug for 2 or more consecutive days). Self-reported recent consumption of mephedrone was confirmed by toxicological analysis in all of the 14 participants who submitted a urine sample.
CONCLUSION Mephedrone has a high abuse and health risk liability, with increased tolerance, impaired control and a compulsion to use, the predominant reported dependence symptoms.
DESIGN Cross-sectional structured telephone interview. Setting UK-based drug users associated with the dance music scene.
PARTICIPANTS A total of 100 mephedrone users, recruited through their involvement with the dance music scene.
MEASUREMENTS Assessment of pattern of use, acute and after effects, DSM dependence criteria and gas chromatography-mass spectrometry urinalysis.
FINDINGS Mephedrone consumption results in typical stimulant-related subjective effects: euphoria, increased concentration, talkativeness, urge to move, empathy, jaw clenching, reduced appetite and insomnia. Thirty per cent of the sample potentially met criteria for DSM-IV dependence and there was evidence of a strong compulsion to use the drug (47% had used the drug for 2 or more consecutive days). Self-reported recent consumption of mephedrone was confirmed by toxicological analysis in all of the 14 participants who submitted a urine sample.
CONCLUSION Mephedrone has a high abuse and health risk liability, with increased tolerance, impaired control and a compulsion to use, the predominant reported dependence symptoms.
Affiliation :
Addictions Department, Institute of Psychiatry, King's College London, United Kingom