Historique
Article de Périodique
Dilated cardiomyopathy and cocaine abuse. Report of two cases (1986)
Auteur(s) :
WIENER, R. S. ;
LOCKHART, J. T. ;
SCHWARTZ, R. G.
Année
1986
Page(s) :
699-701
Sous-type de document :
Etude de cas
Langue(s) :
Anglais
Refs biblio. :
18
Domaine :
Drogues illicites
Discipline :
PAT (Pathologie organique / Organic pathology)
Thésaurus géographique
ETATS-UNIS
Thésaurus mots-clés
ETUDE DE CAS
;
COCAINE
;
COEUR
;
PATHOLOGIE ORGANIQUE
;
INFARCTUS
;
SYMPTOME
Résumé :
Two young patients with dilated cardiomyopathies associated with long-term use of cocaine are described. A 42-year-old male cocaine abuser with normal coronary arteries experienced recurrent myocardial infarction, with development of a dilated, globally hypocontractile left ventricle. The second patient, a 28-year-old woman with a prominent history of inhaling vaporized cocaine ("free-basing"), presented with symptoms and signs of biventricular heart failure and was found to have a dilated cardiomyopathy. The clinical spectrum of cocaine cardiotoxicity is reviewed, and pathophysiologic mechanisms of cocaine-induced cardiomyopathy are discussed. Long-term cocaine use may cause dilated cardiomyopathy and recurrent myocardial infarction, even in the absence of atherosclerotic epicardial coronary artery disease.
Affiliation :
USA