Historique
Article de Périodique
Therapeutic aspects of cannabis and cannabinoids (2001)
(Aspects thérapeutiques du cannabis et des cannabinoïdes)
Auteur(s) :
ROBSON, P.
Année
2001
Page(s) :
107-115
Langue(s) :
Anglais
Refs biblio. :
57
Domaine :
Drogues illicites / Illicit drugs
Thésaurus mots-clés
CANNABIS
;
CANNABINOIDES
;
USAGE THERAPEUTIQUE
;
EFFET SECONDAIRE
Thésaurus géographique
ROYAUME-UNI
Résumé :
Background: Review commissioned in 1996 by the Department of Health (DOH). Aims: Assess therapeutic profile of cannabis and cannabinoids.
Method: Medline search, references supplied by DOH and others, and personal communications.
Results and Conclusions: Cannabis and some cannabinoids are effective anti-emetics and analgesics and reduce intra-ocular pressure. There is evidence of symptom relief and improved well-being in selected neurological conditions, AIDS and certain cancers. Cannabinoids may reduce anxiety and improve sleep. Anticonvulsant activity requires clarification. Other properties identified by basic research await evaluation. Standard treatments for many relevant disorders are unsatisfactory. Cannabis is safe in overdose but often produces unwanted effects, typically sedation, intoxication, clumsiness, dizziness, dry mouth, lowered blood pressure or increased heart rate. The discovery of specific receptors and natural ligands may lead to drug developments. Research is needed to optimise dose and route of administration, quantify therapeutic and adverse effects, and examine interactions.
Method: Medline search, references supplied by DOH and others, and personal communications.
Results and Conclusions: Cannabis and some cannabinoids are effective anti-emetics and analgesics and reduce intra-ocular pressure. There is evidence of symptom relief and improved well-being in selected neurological conditions, AIDS and certain cancers. Cannabinoids may reduce anxiety and improve sleep. Anticonvulsant activity requires clarification. Other properties identified by basic research await evaluation. Standard treatments for many relevant disorders are unsatisfactory. Cannabis is safe in overdose but often produces unwanted effects, typically sedation, intoxication, clumsiness, dizziness, dry mouth, lowered blood pressure or increased heart rate. The discovery of specific receptors and natural ligands may lead to drug developments. Research is needed to optimise dose and route of administration, quantify therapeutic and adverse effects, and examine interactions.
Affiliation :
Warneford Hosp., Oxford, UK
Cote :
A00435