Historique
Article de Périodique
Low-to-moderate alcohol consumption and breast cancer risk by age 50 years among women in Germany (2001)
Auteur(s) :
KROPP S. ;
BECHER, H. ;
NIETERS A. ;
CHANG-CLAUDE J.
Année
2001
Page(s) :
624-634
Langue(s) :
Anglais
Refs biblio. :
51
Domaine :
Alcool / Alcohol
Discipline :
PAT (Pathologie organique / Organic pathology)
Thésaurus mots-clés
SEXE FEMININ
;
CANCER
;
GLANDE MAMMAIRE
;
ALCOOL
;
TYPE D'USAGE
;
FACTEUR DE RISQUE
Thésaurus géographique
ALLEMAGNE
Résumé :
Studies of the association between alcohol drinking and breast cancer show a tendency towards an increase in risk for high consumption levels but yield less consistent results for low-to-moderate levels, particularly among premenopausal women. In a population-based case-control study in Germany, the authors determined the effect of alcohol consumption at low-to-moderate levels on breast cancer risk among women up to age 50 years. The study included 706 case women whose breast cancer had been newly diagnosed in 1992–1995 and 1,381 residence- and age-matched controls. In multivariate conditional logistic regression analysis, the adjusted odds ratios for breast cancer were 0.71 (95% confidence interval (CI): 0.54, 0.91) for average ethanol intake of 1–5 g/day, 0.67 (95% CI: 0.50, 0.91) for intake of 6–11 g/day, 0.73 (95% CI: 0.51, 1.05) for 12–18 g/day, 1.10 (95% CI: 0.73, 1.65) for 19–30 g/day, and 1.94 (95% CI: 1.18, 3.20) for ?31 g/day. The association with high daily ethanol intake of ?19 g was modified by educational level, such that odds ratios were 3.7, 1.6, and 0.7 for women with low, moderate, and high levels of education, respectively. These data suggest that low-level consumption of alcohol does not increase breast cancer risk in premenopausal women.
Affiliation :
Etats-Unis. United States.