Historique
Article de Périodique
A comparative naturalistic study on opiates withdrawal (2003)
(Etude comparative naturalistique sur le sevrage des opiacés)
Auteur(s) :
MODESTIN, J. ;
LIPP P. J. ;
RUESCH P. ;
HATTENSCHWILER J. ;
HELL D.
Année
2003
Page(s) :
238-242
Langue(s) :
Anglais
Refs biblio. :
14
Domaine :
Drogues illicites / Illicit drugs
Thésaurus géographique
SUISSE
Thésaurus mots-clés
OPIACES
;
SYNDROME DE SEVRAGE
;
METHADONE
;
BENZODIAZEPINES
;
COMPARAISON
;
ENQUETE
Note générale :
Journal of Substance Use, 2003, 8, (4), 238-242
Note de contenu :
tabl.
Résumé :
ENGLISH :
Aims. The effectiveness of locally newly introduced methadone-supported heroin withdrawal was evaluated under naturalistic conditions. Design. The corresponding data of 35 patients were compared with data of 31 patients hospitalized in the same setting 3 years ago who were mostly prescribed sedatives (neuroleptics and benzodiazepines) during their heroin withdrawal. Findings. No significant differences between the groups were found with regard to the irregular treatment termination, relapse frequency and clinical global impressions ratings. In one month post-discharge period frequent abuse of heroin decreased in both groups; in the nonmethadone group, frequent abuse of cocaine and alcohol was also reduced. The sedatives-supported heroin withdrawal group showed more distress initially followed by a rapid amelioration; in the methadone group there was less distress initially but the patients did not feel much better on day 10. Conclusions. Methadone-supported heroin withdrawal lasts longer and we failed to demonstrate its advantage over traditional (neuroleptics- and benzodiazepines-supported) withdrawal except for less subjective distress at the withdrawal beginning. (Review' s abstract)
Affiliation :
Dpt of Psychiatry, Univ. of Zurich, Lenggstrasse 31, 8029 Zurich
Suisse. Switzerland.
Suisse. Switzerland.
Cote :
Abonnement