Historique
Périodique
Can HIV-1-contaminated syringes be disinfected? Implications for transmission among injection drug users
Auteur(s) :
ABDALA, N. ;
GLEGHORN A. A. ;
CARNEY, J. M. ;
HEIMER, R.
Année
2001
Page(s) :
487-494
Langue(s) :
Anglais
Refs biblio. :
31
Domaine :
Drogues illicites / Illicit drugs
Discipline :
MAL (Maladies infectieuses / Infectious diseases)
Thésaurus géographique
ETATS-UNIS
Thésaurus mots-clés
VIH
;
INJECTION
;
SERINGUE
;
EAU DE JAVEL
;
EFFICACITE
;
PREVENTION
;
EPIDEMIOLOGIE
Note générale :
Journal of Acquired Immune Deficiency Syndromes, 2001, 28, (5), 487-494
Résumé :
ENGLISH :
Bleaching of syringes has been advocated to prevent HIV-1 transmission among injection drug users (IDUs). Bleach is frequently distributed by needle exchange, outreach, and educational programs targeting IDUs. We applied a sensitive HIV-1 microculture assay to determine the effectiveness of bleach in disinfecting syringes contaminated with HIV-1. This study demonstrates that in a laboratory environment designed to replicate injection behaviors, undiluted bleach is highly effective in reducing the viability of HIV-1 even after minimal contact time. However, it did not reduce the HIV-1 recovery to zero. Furthermore, three washes with water were nearly as effective as a single rinse with undiluted bleach in reducing the likelihood that contaminated syringes harbored viable HIV-1. Given the reality that IDUs share syringes and may not have access to a new, sterile syringe for each injection, the results suggest that they should be encouraged through harm reduction interventions to clean their syringes, preferably with undiluted bleach. (Review' s abstract)
Affiliation :
Dpt of Epidemiology and Public Health, Yale Univ. School of Medicine, New Haven, Connecticut 06520-8034
Etats-Unis. United States.
Etats-Unis. United States.
Cote :
A01599