Historique
Article de Périodique
The neurobiology of opioid dependence: implications for treatment (2002)
(Aspects neurobiologiques de la dépendance aux opiacés : implications en matière de traitement.)
Auteur(s) :
KOSTEN, T. R. ;
GEORGE, T. P.
Année
2002
Page(s) :
13-21
Langue(s) :
Français
Refs biblio. :
24
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
HEROINE
;
OPIACES
;
NEUROBIOLOGIE
;
MECANISME D'ACTION
;
POTENTIEL ADDICTIF
;
USAGE REGULIER
;
SUBSTITUTION
;
TRAITEMENT
Note générale :
Science and Practice Perspectives, 2002, 1, (1), 13-21
Note de contenu :
graph.
Résumé :
ENGLISH :
Opioid tolerance, dependence, and addiction are all manifestations of brain changes resulting from chronic opioid abuse. The opioid abuser's struggle for recovery is in great part a struggle to overcome the effects of these changes. Medications such as methadone, LAAM, buprenorphine, and naltrexone act on the same brain structures and processes as addictive opioids, but with protective or normalizing effects. Despite the effectiveness of medications, they must be used in conjunction with appropriate psychosocial treatments. (Author' s abstract)
Affiliation :
Yale Univ. School of Medicine, New Haven, Connecticut
Etats-Unis. United States.
Etats-Unis. United States.
Cote :
R00128