Historique
Article de Périodique
Neuropsychiatric consequences (atypical psychosis and complex-partial seizures) of ecstasy use: possible evidence for toxicity-vulnerability predictors and implications for preventative and clinical care (2003)
Auteur(s) :
VECELLIO, M. ;
SCHOPPER C. ;
MODESTIN J. H. C.
Année
2003
Page(s) :
163-167
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PSY (Psychopathologie / Psychopathology)
Thésaurus mots-clés
ETUDE DE CAS
;
TROUBLE BIPOLAIRE
;
EPILEPSIE
;
MDMA-ECSTASY
;
PSYCHOSE
;
PARANOIA
;
NEUROPSYCHIATRIE
;
TOXICITE
;
FACTEUR DE VULNERABILITE
Thésaurus géographique
SUISSE
Résumé :
Two case reports of ecstasy abuse and its serious neuropsychiatric complications are presented. The first patient developed a florid paranoid psychosis resembling schizophrenia after repeated long-term recreational ecstasy abuse, and significant alterations with intermittent paroxysmal discharges were found in his electroencephalogram. The second patient showed an atypical paranoid psychosis with Fregoli syndrome and a series of complex-partial epileptic seizures with secondary generalization after a first single ecstasy dose. Both subjects presented considerable vulnerability; the first a minimal brain dysfunction after perinatal asphyxia and a persisting attention deficit/hyperactivity disorder, the second a long-lasting opioid addiction. In vulnerable individuals, dose-independent ecstasy abuse can lead to unpredictable and potentially dangerous neuropsychiatric sequelae which require proper initial assessment and adequate treatment.
Affiliation :
Psychiatric University Hospital Zurich, Zürich
Suisse. Switzerland.
Suisse. Switzerland.
Cote :
A01875