Historique
Article de Périodique
Long-term outcome of chronic drug use: The Amsterdam Cohort Study among Drug Users (2005)
(Résultats à long terme de l'usage chronique de drogues : étude de la cohorte d'Amsterdam chez les usagers de drogues)
Auteur(s) :
TERMORSHUIZEN F. ;
KROL A. ;
PRINS, M. ;
AMEIJDEN, E.
Année
2005
Page(s) :
271-279
Langue(s) :
Anglais
Refs biblio. :
27
Domaine :
Drogues illicites / Illicit drugs
Discipline :
EPI (Epidémiologie / Epidemiology)
Thésaurus géographique
PAYS-BAS
Thésaurus mots-clés
DEPENDANCE
;
ENQUETE
;
HEROINE
;
COCAINE
;
AMPHETAMINE
;
MORTALITE
;
PREVALENCE
;
TRAJECTOIRE
;
ETUDE LONGITUDINALE
;
METHADONE
;
ABSTINENCE
;
MOTIVATION
;
REDUCTION DES RISQUES ET DES DOMMAGES
;
EPIDEMIOLOGIE ANALYTIQUE
;
TYPE D'USAGE
Résumé :
In the present study, mortality rates and prevalence of abstinence from illicit drugs among persons with a history of addiction to heroin, cocaine, and/or amphetamines were estimated along the drug-using career time scale. Follow-up data on drug use and vital status were analyzed for participants in the Amsterdam Cohort Study among Drug Users (n = 899; 19852002). Participants in the study were primarily recruited at low-threshold methadone outposts. It was estimated that at least 27% of drug users had died within 20 years after starting regular drug use; for half, death had been due to causes unrelated to human immunodeficiency virus. A favorable trend towards abstinence with increasing time since initiation of regular use was observed. However, among those alive, the estimated prevalence of abstinence for at least 4 months from the above drugs and methadone was only 27% at 20 years since initiation. A higher age at initiation, a calendar year of initiation before 1980, and a Western European ethnic origin were associated with higher prevalence of abstinence. These results indicate that the concept of "maturing out" to a drug-free state does not apply to the majority of drug users. Further studies on determinants of individual transitions in drug use are important in order to establish evidence-based intervention strategies.
Affiliation :
Pays-Bas. Netherlands.