Historique
Article de Périodique
HIV incidence among injection drug users in New York City, 1990 to 2002: Use of serologic test algorithm to assess expansion of HIV prevention services (2005)
Auteur(s) :
DES JARLAIS, D. C. ;
PERLIS.T. ;
ARASTEH, K. ;
TORIAN L. ;
BEATRICE, S. ;
MILLIKEN J. ;
MILDVAN D. ;
YANCOVITZ S. ;
FRIEDMAN, S.
Année
2005
Page(s) :
1439-1444
Langue(s) :
Anglais
Refs biblio. :
25
Domaine :
Drogues illicites / Illicit drugs
Discipline :
MAL (Maladies infectieuses / Infectious diseases)
Thésaurus mots-clés
VIH
;
INJECTION
;
TEST
;
ECHANGE DE SERINGUES
;
ETUDE TRANSVERSALE
;
EVALUATION
;
ETUDE RETROSPECTIVE
Thésaurus géographique
ETATS-UNIS
Résumé :
Objectives. We sought to estimate HIV incidence among injection drug users (IDUs) in New York City from 1990 to 2002 to assess the impact of an expansion of syringe exchange services. Syringe exchange increased greatly during this period, from 250000 to 3000000 syringes exchanged annually. Methods. Serum samples were obtained from serial cross-sectional surveys of 3651 IDUs. HIV-positive samples were tested with the Serologic Test Algorithm for Recent HIV Seroconversion (STARHS) assay to identify recent HIV infections and to estimate HIV incidence. Consistency with other incidence studies was used to assess strengths and limitations of STARHS. Results. HIV incidence declined from 3.55/100 person-years at risk (PYAR) from 19901992, to 2.63/100 PYAR from 19931995, to 1.05/100 PYAR from 19961998, and to 0.77/100 PYAR from 19992002 (P<.001). There was a very strong negative linear relationship (r= .99, P<.005) between the annual numbers of syringes exchanged and estimated HIV incidence. These results were highly consistent with a large number of shorter incidence studies among IDUs conducted during the time period. Conclusions. STARHS testing of samples from large serial cross-sectional surveys can provide important data for the assessment of community-level HIV prevention.
Affiliation :
Beth Israel Medical Center, New York, NY, USA
Cote :
Abonnement