Historique
Article de Périodique
Can drug design inhibit abuse ? (2005)
(La forme du médicament peut-elle limiter son abus ?)
Auteur(s) :
COLEMAN, J. J. ;
BENSINGER, P. B. ;
GOLD, M. S. ;
SMITH, D. E. ;
BIANCHI, R. P. ;
DUPONT, R. L.
Année
2005
Page(s) :
343-362
Langue(s) :
Anglais
Refs biblio. :
106
Domaine :
Drogues illicites / Illicit drugs
Thésaurus mots-clés
DISTRIBUTION CONTROLEE
;
TRAITEMENT
;
PRESCRIPTION MEDICALE
;
ABUS
;
MEDICAMENTS
Note générale :
Journal of Psychoactive Drugs, 2005, 37, (4), 313-362
Note de contenu :
tabl.
Résumé :
ENGLISH :
A recent federal report indicates that prescription drug abuse is now the second leading category of illicit drug use, following marijuana use. Control strategies typically focus on reducing the diversion of prescription drugs from legitimate sources. The proliferation of unregulated Internet sources, however, has rendered control strategies less effective. This study examines a new approach that focuses on reducing abusability through the use of abuse-resistant drug designs. Drugs with and without such designs are compared and abuse levels assessed using multiple sources. In every instance, drugs employing abuse-resistant designs were found to have significantly lower levels of abuse than comparator drugs without such designs.
Affiliation :
Prescription Drug Res. Ctr, 4031 Univ. Drive, Suite 200, Fairfax, VA 22030. Email : jcoleman@pdrcllc.com
Etats-Unis. United States.
Etats-Unis. United States.
Cote :
Abonnement