Historique
Périodique
Methylone and mCPP, two new drugs of abuse?
Auteur(s) :
BOSSONG, M. G. ;
VAN DIJK, J. P. ;
NIESINK, R. J. M.
Année
2005
Page(s) :
321-323
Langue(s) :
Anglais
Domaine :
Drogues illicites / Illicit drugs
Discipline :
PRO (Produits, mode d'action, méthode de dépistage / Substances, action mode, screening methods)
Thésaurus mots-clés
DROGUES DE SYNTHESE
;
MECANISME D'ACTION
;
mCPP
;
MDMA-ECSTASY
;
METHYLONE
;
PHARMACOLOGIE
;
NEUROBIOLOGIE
Note générale :
Addiction Biology, 2005, 10, (4), 321-323
Résumé :
ENGLISH :
Recently, two new ecstasy-like substances, methylone and mCPP, were found in street drugs in the Netherlands by the Drugs Information and Monitoring System (DIMS). Methylone (3,4-methylenedioxymethcathinone) is the main ingredient of a new liquid designer drug that appeared on the Dutch drug market, called 'Explosion'. mCPP (meta-chlorophenylpiperazine) is a substance often used as a probe for the serotonin function in psychiatric research, and has now been found in street drugs, both in tablets and powders. Methylone as well as mCPP act on monoaminergic systems, resembling MDMA (3,4-methylenedioxymethamphetamine), with mCPP mainly affecting the serotonin system. The subjective effects of both new substances exhibit subtle differences with those of MDMA. Only little is known about the harmfulness of both methylone and mCPP. However, because of similarities between these substances and MDMA, risks common to MDMA cannot be excluded.
Affiliation :
Drugs Information and Monitoring System (DIMS), Trimbos Institute for Mental Health and Addiction, Utrecht. Email : mbossong@trimbos.nl
France. France.
France. France.
Cote :
A02675