Historique
Article de Périodique
Managing opioid addiction with buprenorphine (2006)
(Prendre en charge la dépendance aux opiacés avec la buprénorphine)
Auteur(s) :
DONAHER P. A. ;
WELSH, C.
Année
2006
Page(s) :
573-578
Sous-type de document :
Revue de la littérature / Literature review
Langue(s) :
Anglais
Refs biblio. :
29
Domaine :
Drogues illicites / Illicit drugs
Thésaurus mots-clés
PRISE EN CHARGE
;
OPIACES
;
RECOMMANDATION
;
BUPRENORPHINE
;
TRAITEMENT DE MAINTENANCE
;
MEDECIN GENERALISTE
;
PRESCRIPTION MEDICALE
;
POSOLOGIE
Note générale :
Editorial : "Buprenorphine: Effective treatment of opioid addiction starts in the office", Fiellin D.A., p.1513-4.
Résumé :
Legislation has enabled physicians to treat opioid-dependent patients with an office-based maintenance program using buprenorphine, a partial mu-opioid receptor agonist. Clinical studies indicate buprenorphine effectively manages opioid addiction. Buprenorphine is more effective than placebo for managing opioid addiction but may not be superior to methadone if high doses are needed. It is comparable to lower doses of methadone, however. Treatment phases include induction, stabilization, and maintenance. Buprenorphine therapy should be initiated at the onset of withdrawal symptoms and adjusted to address withdrawal symptoms and cravings. Advantages of buprenorphine include low abuse potential and high availability for office use. Disadvantages include high cost and possible lack of effectiveness in patients who require high methadone doses. Most family physicians are required to complete eight hours of training before they can prescribe buprenorphine for opioid addiction.
Affiliation :
Whitsett Center, Chestertown, MD, USA
Cote :
A02711